Protein Info for MMP_RS00235 in Methanococcus maripaludis S2

Annotation: HDIG domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 195 TIGR00277: HDIG domain" amino acids 41 to 120 (80 residues), 51 bits, see alignment E=5.2e-18 PF01966: HD" amino acids 48 to 154 (107 residues), 50 bits, see alignment E=1.7e-17

Best Hits

KEGG orthology group: K06950, uncharacterized protein (inferred from 100% identity to mmp:MMP0037)

Predicted SEED Role

"metal-dependent phosphohydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M180 at UniProt or InterPro

Protein Sequence (195 amino acids)

>MMP_RS00235 HDIG domain-containing protein (Methanococcus maripaludis S2)
MNIVLNDLLNDATLYEKFSNFKKMQEIPNFNEYLTFLTERCEKNVVLHSIAVADYVYEFG
IKLLNKKYDFDLDTAVLGAILHDIGRSKSHNIDHGIIGSEILLKNNFNEKYAKIAERHIG
AGISRKEAEDLNLPKKDYIPKTLEEKVIANADNLVSGHIRVDIDFVIDKFKKRTNNEVSN
KVYALYLEINKLIDN