Protein Info for MMJJ_RS08485 in Methanococcus maripaludis JJ

Annotation: Lrp/AsnC family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 140 PF13404: HTH_AsnC-type" amino acids 1 to 42 (42 residues), 52.8 bits, see alignment E=5.7e-18 PF13412: HTH_24" amino acids 1 to 48 (48 residues), 50.6 bits, see alignment E=2.3e-17 PF22451: NirdL-like_HTH" amino acids 18 to 47 (30 residues), 27.1 bits, see alignment 5.2e-10 PF01037: AsnC_trans_reg" amino acids 71 to 138 (68 residues), 49 bits, see alignment E=9e-17

Best Hits

Swiss-Prot: 76% identical to PTR2_METJA: HTH-type transcriptional regulator Ptr2 (ptr2) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K03718, Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA (inferred from 97% identity to mmx:MmarC6_1531)

Predicted SEED Role

"HTH-type transcriptional regulator Ptr2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (140 amino acids)

>MMJJ_RS08485 Lrp/AsnC family transcriptional regulator (Methanococcus maripaludis JJ)
MDEKDMKILDFLITDGRKPFTEIAKELKTSESSVRKRVKKMEEEGVIKGYSVMVDTPKMG
YNVVAQTGFDTNPEDFLAVAQELCKFEEVKKVFTSTGDHMIMTEIWAKDGKELSEIIFNK
IGKIKGIKKVCPAIILEQLK