Protein Info for MMJJ_RS06885 in Methanococcus maripaludis JJ

Annotation: EhaF family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 157 transmembrane" amino acids 20 to 37 (18 residues), see Phobius details amino acids 132 to 150 (19 residues), see Phobius details PF09879: DUF2106" amino acids 3 to 151 (149 residues), 235.2 bits, see alignment E=1.1e-74

Best Hits

Swiss-Prot: 61% identical to Y524_METJA: Uncharacterized protein MJ0524 (MJ0524) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K14097, energy-converting hydrogenase A subunit F (inferred from 99% identity to mmp:MMP1453)

Predicted SEED Role

"Energy conserving hydrogenase Eha transmembrane protein F"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (157 amino acids)

>MMJJ_RS06885 EhaF family protein (Methanococcus maripaludis JJ)
MKKLNEAWNYISKPSAVSRLFAGFVCIVLFIGIFLPTEFTSDQLYPKNAIQGQVLKTPLA
PYDRGGVVLSEPADIKSQYPEYQSIRGQITAYLSPVAIAISENTMYFGTTIVSTPGGILD
EILYYTRGFDTVLESLTLLLSFTIFGWLFLNRNNKVK