Protein Info for MMJJ_RS04105 in Methanococcus maripaludis JJ

Annotation: prepilin peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 31 to 52 (22 residues), see Phobius details amino acids 58 to 77 (20 residues), see Phobius details amino acids 96 to 119 (24 residues), see Phobius details amino acids 132 to 151 (20 residues), see Phobius details amino acids 156 to 172 (17 residues), see Phobius details amino acids 182 to 201 (20 residues), see Phobius details amino acids 207 to 228 (22 residues), see Phobius details amino acids 322 to 344 (23 residues), see Phobius details PF01478: Peptidase_A24" amino acids 14 to 115 (102 residues), 35.9 bits, see alignment E=8.7e-13 PF06819: Arc_PepC" amino acids 210 to 316 (107 residues), 136.2 bits, see alignment E=5.3e-44

Best Hits

Swiss-Prot: 53% identical to Y83C_METJA: Uncharacterized protein MJ0835.2 (MJ0835.2) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K07991, archaeal preflagellin peptidase FlaK (inferred from 98% identity to mmp:MMP0232)

Predicted SEED Role

"Uncharacterized protein MJ0835.2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (346 amino acids)

>MMJJ_RS04105 prepilin peptidase (Methanococcus maripaludis JJ)
MFGFDNLILGVYLFNFLLILTATYTDIKERIIPHFVIILMLIVNLPLGYYFFGFDAITSF
FATLILCLILGVGMGGGDVKMFTALSPLFAAETIYFVPKNILILIGLSALFAAIFPMTKI
LKNYWKDIVPSSAYLAMLIGIIVSITEIYSIGNTKTILWIYIILSIFISRKIPKYRIISN
KLGYITPIYLVGFYLLNPAYFVSENVLISFFVYIGQLSLISLVIYALTGAEISSKKQISD
LKEGDIIRDIVTIKENGEVTVENANILKRFKHMIYGEMGKLEGKSLMTDGEGLSDENLEL
LNKLQNEGKIGGELNVLTTYPFVPFVLVAYCVITLLNMGFINYLVG