Protein Info for MMJJ_RS01830 in Methanococcus maripaludis JJ

Annotation: tRNA(Ile)(2)-agmatinylcytidine synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 424 PF22641: TiaS_TCKD" amino acids 2 to 144 (143 residues), 87.7 bits, see alignment E=1.7e-28 PF08489: TiaS_FLD" amino acids 146 to 255 (110 residues), 128.2 bits, see alignment E=3.5e-41 PF01336: tRNA_anti-codon" amino acids 282 to 343 (62 residues), 34.9 bits, see alignment E=2.3e-12 PF23783: Zn_ribbon_TiaS" amino acids 353 to 394 (42 residues), 28.6 bits, see alignment 1.9e-10

Best Hits

Swiss-Prot: 61% identical to TIAS_METJA: tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS (tiaS) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K06932, (no description) (inferred from 97% identity to mmp:MMP0616)

Predicted SEED Role

"OB-fold nucleic acid binding domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (424 amino acids)

>MMJJ_RS01830 tRNA(Ile)(2)-agmatinylcytidine synthase (Methanococcus maripaludis JJ)
MYIGIDDTDSREHYCTTYVGTILQEELQKTYLMDTPKLIRMNPMVKYKTRGNGGVCLRII
EDEKKLNESEIESIKKLVIETVEKFSDFDCENTNPGIVFLSEENYQKNQKTLLNYYNSVL
YDILKVNDSEKILNEIGAEYIKYKKGHGIIGALGAIASKPPFTYELLAYRKSEKWGTERE
IDIDSIIKMDTDTFPFTFNNIDGKKSIITPHTPCPVLYGIRGISREILEKAKNTVKSDEV
DKCQLYITNQGTDVHLKFSKINDIYPDTGVISYGKIVENPKEITGGHVLFKLKDDTGEID
CIAYEPTKEFRNIVRKLNCGDLVGVYGTVREDPFEINIEKLKIVTLQKIYEKNKFCECGG
TLKAKGLKSGYKCNICGKRVNYNQIKLNEVKRGIKEGFYEVPPSARRHLSKPIVLYDFDL
ENIK