Protein Info for MMJJ_RS01205 in Methanococcus maripaludis JJ

Annotation: DNA adenine methylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00571: DNA adenine methylase
  • amino acids 6 to 303 (298 residues), 272.4 bits, E=2.4e-85
• PF02086: MethyltransfD12
  • amino acids 11 to 277 (267 residues), 199.9 bits, E=3e-63

Best Hits

Swiss-Prot: 54% identical to MTM3_METJA: Modification methylase MjaIII (mjaIIIM) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K06223, DNA adenine methylase [EC: 2.1.1.72] (inferred from 98% identity to mmp:MMP0735)

Predicted SEED Role

"Modification methylase MjaIII (EC 2.1.1.72)" (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Protein Sequence (306 amino acids)

>MMJJ_RS01205 DNA adenine methylase (Methanococcus maripaludis JJ)
MHRKAKPFLKWAGGKRRLLTQFEDHYPEGLKNGKIKKYVEPFLGGGAVYLGLQSKYKFKK
VVLNDINHELMLSYKTVQNNIDELISILKPIEENFNKMNFESQKMQYYKIRNEYNIEKSN
IDKNKSENIIENVARFIFLNKTCFNGLYRLNKKGMFNVPFGRYLRPRIFDEPTLRGVNKA
LKGVKLLCDDYKGVEKHISIDKETFVYIDPPYRPLPETVSFTSYSKEDFLEKDQVDLSNW
FKYLDKKGAYLMLSNSDPTNTNPKDRFFEDHYGGFNIDKVCAGRIINSRVNGRRKITELV
IKNYPK