Protein Info for LRK55_RS17920 in Rhodanobacter denitrificans MT42

Annotation: UTP--glucose-1-phosphate uridylyltransferase GalU

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01099: UTP--glucose-1-phosphate uridylyltransferase
  • amino acids 5 to 269 (265 residues), 337.7 bits, E=2.6e-105
• PF00483: NTP_transferase
  • amino acids 13 to 273 (261 residues), 107 bits, E=6.1e-35

Best Hits

KEGG orthology group: K00963, UTP--glucose-1-phosphate uridylyltransferase [EC: 2.7.7.9] (inferred from 70% identity to smt:Smal_1652)

Predicted SEED Role

"UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9)" (EC 2.7.7.9)

MetaCyc Pathways

• colanic acid building blocks biosynthesis (11/11 steps found)
• superpathway of anaerobic sucrose degradation (16/19 steps found)
• UDP-α-D-glucose biosynthesis (2/2 steps found)
• sucrose biosynthesis I (from photosynthesis) (7/9 steps found)
• sucrose degradation II (sucrose synthase) (4/5 steps found)
• superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis (4/6 steps found)
• stachyose degradation (4/7 steps found)
• sucrose biosynthesis II (4/8 steps found)
• type I lipoteichoic acid biosynthesis (S. aureus) (5/17 steps found)

KEGG Metabolic Maps

• Galactose metabolism
• Nucleotide sugars metabolism
• Pentose and glucuronate interconversions
• Starch and sucrose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.9

Protein Sequence (291 amino acids)

>LRK55_RS17920 UTP--glucose-1-phosphate uridylyltransferase GalU (Rhodanobacter denitrificans MT42)
MSKPLRKVVFPVAGLGTRFLPATKVVAKEMLPVLDKPLIQYAVDEAVDAGADTLVFVTNR
YKHAIADYFDKAYELESKLHEKGKAELLALVQGTLPRHVRAIFVTQPEALGLGHAVLCAK
PVVGDEPFGVILPDDLIWNGSGKGALRQMAELADAQGAGVIAVEEVPHDQTDKYGIVDAV
PVDERSALIRHMVEKPKPADAPSNLAVVGRYVLPGRIFQLLEQTTPGAGGEIQLTDAIDA
LLKEQGKVLAYRFEGTRFDCGNKAGLVRATMHMAMQDPKLAPTVREFLGQL