Protein Info for LRK55_RS17495 in Rhodanobacter denitrificans MT42

Annotation: DNA translocase FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 774 transmembrane" amino acids 27 to 45 (19 residues), see Phobius details amino acids 75 to 96 (22 residues), see Phobius details amino acids 114 to 134 (21 residues), see Phobius details amino acids 140 to 160 (21 residues), see Phobius details amino acids 167 to 186 (20 residues), see Phobius details PF13491: FtsK_4TM" amino acids 20 to 193 (174 residues), 153.5 bits, see alignment E=1.1e-48 PF17854: FtsK_alpha" amino acids 273 to 373 (101 residues), 99.6 bits, see alignment E=2.6e-32 PF01580: FtsK_SpoIIIE" amino acids 381 to 595 (215 residues), 261.2 bits, see alignment E=1.8e-81 PF01935: DUF87" amino acids 409 to 457 (49 residues), 25.8 bits, see alignment 2.7e-09 PF09397: FtsK_gamma" amino acids 709 to 768 (60 residues), 89.5 bits, see alignment 2.4e-29

Best Hits

Swiss-Prot: 72% identical to FTSK_XANCP: DNA translocase FtsK (ftsK) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K03466, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family (inferred from 74% identity to psu:Psesu_1542)

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (774 amino acids)

>LRK55_RS17495 DNA translocase FtsK (Rhodanobacter denitrificans MT42)
MARSTNVRQPPKEGLSEELKRRLREAGALLLLPLALYLLVCLFSYNPHDPSWTNAGQLEH
ARNFGGTVGAYIADLLRWIFGLVAYCFPLLLLLLGVQVLRQRGEQAVHPWEPALRLIGFV
FFFITGPALLYLNFHDEPVLPQGVGGIIGVWVGDALLSAFGDKGAPLLLLALFLIAVTLA
TGLSWFKVMDWTGHGVLKLLDWLKGKLREAPQALAARQARTEREVVKKADAVRQAKREPV
RIEAPPAPVTKSERAKLETQIPLFVGAAVPGELPPLSLLDEAPPQGPGYSEETLEVLSRQ
VEFKLKDFKIDVKVVGAYPGPVITRFEMEPAPGIRGSQVSSLDKDIARGLSVVSVRVVDV
IPGKNVIGLEIPNTHKQIVYLSEILRSDKYDQTKSPLSLALGKDIGGKPVVVDLAKMPHL
LVAGTTGSGKSVAVNAMVLSLLYKASPKDVRMIMIDPKMLELSVYEGIPHLLAPVVTDMK
EAANALRWCVAEMERRYKLMAAVGVRNLAGFNKKVRDAENAGQPLLDPLFRPNPEMPNLA
AEPLEPLPYIVVFIDEFADMMMIVGKKVEELIARLAQKARAAGVHLILATQRPSVDVITG
LIKANIPTRIAFQVSSKIDSRTILDQSGAETLLGHGDMLYLPPGTATPERVHGAFVDDHE
VHHVVAWLKSQGAPNYIEGVLEEAQPTSDGKFINDSGLPQEGEEGGDADTQLYDKAVAIV
TQTRRASISGVQRHLRIGYNRAARLVEQMEQDGVVSAPQHNGNREVLAPPPPKN