Protein Info for LRK55_RS16265 in Rhodanobacter denitrificans MT42

Annotation: penicillin acylase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 743 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details PF01804: Penicil_amidase" amino acids 54 to 732 (679 residues), 402.1 bits, see alignment E=3.8e-124

Best Hits

KEGG orthology group: K07116, (no description) (inferred from 68% identity to ccr:CC_1122)

Predicted SEED Role

"Penicillin amidase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (743 amino acids)

>LRK55_RS16265 penicillin acylase family protein (Rhodanobacter denitrificans MT42)
MHMHTANESRPRAPWRRLPRPLLAVALLAYGLLAGAQAAPPTGQVRWQRQAQAVTITRDD
WGIAHVHGRTDADAVFGMAYAQAEDDFNRVETNYLNSLGRLAEAEGESAIWSDLRQQLFI
DPVELKALYAKSPAWLQALMNGWADGLNYYLATHPDVHPRVIKHFEPWMALSFSEGSIGG
DIERVSLEQLAAFYGTDGKQLAGVTTPSSWVEPTGSNGFAIAPKLTADGHALLWINPHTS
FFFRSELQMSSDEGLDAYGAVTWGQFFVYQGFNHHIGWMHTSTGADVVDEFAETIVHQDG
KLFYRYGKELRPVTTRTIHVAYRAKDGTMATRNFDARFTHHGPIVRAADGKWIATALMNK
PLEALEQSWLRTKASDYASYMKVAELKANSSNNTIFADDKGEIAYLHPQFIPRRDNRFDY
TKPVDGSDPATDWQGLHKLDEAPHLLNPPNGWIMNTNNWPYSAAGAFSPKQADYPRYMDS
FGENPRGIHATRVLDRVRDFSQASLISAAFDSYLPAFSRLVPVLVHDYDMLPDNDPLKPR
LAGQIALLRSWDYRWGIASMPTTLAVFWGDMLWDKVHAEAEAEHQSVYDYMAGDAGARAR
LGTLAEASDRLQQDFGSWGVPWGEVNRYQRNDGAIVQKFDDARPSIPVPFVSSRWGSLAS
FGAHRWPGTKRYYGTGGNSFVAVVEFGPKVSARAITAGGESGHPGSKHFNDEAERYTTGN
LRTVYFWPEQLKGHTERVYHPGE