Protein Info for LRK55_RS16030 in Rhodanobacter denitrificans MT42
Annotation: ectonucleotide pyrophosphatase/phosphodiesterase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 46% identity to smt:Smal_1217)Predicted SEED Role
"Alkaline phosphodiesterase I (EC 3.1.4.1) / Nucleotide pyrophosphatase (EC 3.6.1.9)" in subsystem Purine conversions (EC 3.1.4.1, EC 3.6.1.9)
MetaCyc Pathways
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (18/18 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis I (9/9 steps found)
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (12/14 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis III (8/9 steps found)
- dZTP biosynthesis (4/5 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis II (5/7 steps found)
- pyrimidine deoxyribonucleotides dephosphorylation (2/3 steps found)
- tunicamycin biosynthesis (2/9 steps found)
KEGG Metabolic Maps
- Nicotinate and nicotinamide metabolism
- Pantothenate and CoA biosynthesis
- Purine metabolism
- Riboflavin metabolism
- Starch and sucrose metabolism
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.1.4.1 or 3.6.1.9
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (428 amino acids)
>LRK55_RS16030 ectonucleotide pyrophosphatase/phosphodiesterase (Rhodanobacter denitrificans MT42) MKILFRLLLCSLAAFSFGCATQRPAPRATGAATPTGQPVPLLLISIDGYRPDYLQRGLSP TLAMLAQGGVQAASMQPAFPSLTFPNHYTLVTGLTPDHHGVVNNTMFDPQLGKFSLSSRH AISDGRWWAGGTPIWETADQHGLRTGIMFWPGSEADIHGHRPDYWKPFDGNVTPDQRVDQ VLAWLDLPAAERPGFLTLYFDAVDHAGHLYGPDTAQVNAALRETDTALARLVAGLQQRGL FDRINLIVLSDHGMAGVPEANSVLIDQLVPLDRVHTVSLGILAGFNPASDSAAARADFAQ VERTLEQPQPHMQCWDKTRVPARLAYGSNPRVPQLLCLANVHWRITTSEHAAKRKGRLSL GEHGYDNAEPLMQALFVAHGPAFRVGTQLPAFPNVDVYPLMTHLLGLPAAANDGDYDAVK GMLKAAAQ