Protein Info for LRK55_RS14650 in Rhodanobacter denitrificans MT42

Annotation: DNA mismatch repair protein MutS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 902 PF01624: MutS_I" amino acids 19 to 129 (111 residues), 147.5 bits, see alignment E=4.3e-47 PF05188: MutS_II" amino acids 138 to 263 (126 residues), 112.1 bits, see alignment E=6.7e-36 PF05192: MutS_III" amino acids 280 to 600 (321 residues), 161.5 bits, see alignment E=8.4e-51 TIGR01070: DNA mismatch repair protein MutS" amino acids 423 to 899 (477 residues), 664.7 bits, see alignment E=1.2e-203 PF05190: MutS_IV" amino acids 469 to 560 (92 residues), 109 bits, see alignment E=3e-35 PF00488: MutS_V" amino acids 651 to 843 (193 residues), 280.5 bits, see alignment E=1.9e-87

Best Hits

Predicted SEED Role

"DNA mismatch repair protein MutS" in subsystem DNA repair, bacterial MutL-MutS system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (902 amino acids)

>LRK55_RS14650 DNA mismatch repair protein MutS (Rhodanobacter denitrificans MT42)
MIDKNDKEAHADRLATHSPAMRQYLSAKAAHPDVLLFFRMGDFYELFYDDARKAARLLDI
TLTQRGQSGGAPIPMAGVPYHAAENYLARLVRLGESVAICEQMGDPALAKGIVERKVVRV
VTPGTVTDAALLEERRDNLLLAIATGAHGAYGLAWVDLSSGRFLLSEVPNAEALAAELAR
LQPAETLVGEDVAWPKLVSALPGLRKRPPWHFDGDAAKRGLNRFFGTRDLGGFGVDKLPL
AVAAAGCLLGYVEETQKSALPHLTGMAVESASETIALDAATRRNLELDTHPSGRTEHTLL
GVLDETVTPMGARALRRWLTRPLRSREVLRQRHQAIGMLIDSRRGEMLRETLRGIGDLER
ILARVALRSARPRDLSTLRDGLLAAPELTRALVPDRENQEAGVASAIIPDRGNQKAAIHG
RTLQESLGPLLHALVERIGNHADTAALLARAVVEQPPVLQRDGGVIADGYDAELDELRRL
STHADQFLVELEEREKAASGITTLKVGYNRVHGYYIEITRAQSDKAPTHYTRRQTTKNAE
RYITEELKAFEDKVLSAKERSLMRERALYEALLDTLTEKLEPLRTAAAAMAELDVLATLA
ERAEALDWNAPQLTDEPGIAIERGRHPVVEKVRDEPFEPNDLKLDDTRRMLVITGPNMGG
KSTYMRQNALIVLLAHIGSYVPASRAVIGPIDRIFTRIGAGDDLSRGQSTFMVEMSETAN
ILHNATADSLVLMDEVGRGTSTYDGLSLARAAAVHLARHSRAYTLFATHYFELTELANEF
AAIANVHLDAVEYHDKKQGEQLVFMHAVKEGPANRSFGLQVAALAGLPKSVIADAKRTLA
ELERGMHLHASTPAPAAESSPQLGLFAPAQPSAAERMLEAIDPDALSPREALELLYRLKR
SG