Protein Info for LRK55_RS14040 in Rhodanobacter denitrificans MT42

Annotation: penicillin acylase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 804 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details PF01804: Penicil_amidase" amino acids 51 to 788 (738 residues), 462.8 bits, see alignment E=1.7e-142

Best Hits

KEGG orthology group: K01434, penicillin amidase [EC: 3.5.1.11] (inferred from 49% identity to nit:NAL212_1210)

Predicted SEED Role

"Penicillin acylase II"

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (804 amino acids)

>LRK55_RS14040 penicillin acylase family protein (Rhodanobacter denitrificans MT42)
MMVRRRRLLRVLLLALPALLLAAFVTGWYLLAGSRARLDGARPAASLAAAVSITRDALGT
VTIEGKNRADISYALGYVHAQERFFAMDLMRRLSAGELSALVGPAALKVDLDHRRHRLRA
IAAAAYAHLPPAERHQLDRYRDGVNAGLADLRVQPWEYLLLGSRPQPWRAEDSMLVIAAM
YLDLNGDARNERELRMAQMRAVLPGPLVDFLLAPDPDWEAPLRGRLSRSPVLPAADVFDL
RRLAPATGSSTALAAALVPALDAPRPGSNNFAVAGTLTGSGAALLANDMHLGLRVPNIWF
RTRLRYPDPTAPGGRRDVNGVSLPGTPAIIVGSNGQIAWGFTNSYGDWQDWVRVRRDPAD
ASRYRVPDGWAAIETHDEHIQVKGRPDTILKIEDTRWGPIMGTDTDGTPLALAWIGGRPH
GYNLDLMQLEHAPDVATALDLAPHLGMPPQNLLVADSRGEIGWTLAGNSVPLRAGIDPLL
PSDWSRPGSGWQGWAAPASYPRIENPADGRLWTANNRTVDGDALTLLGNGGHDLGARAQQ
IRDDLHARPSFTPGDLLDIQLDDRAVFLSRWQRLLQDTLADSTDPSLQPLRRLTAAWRGR
AAVDSVDYQLVRAFRRQVSAAVLAPFVARVKQRYADFGWPGENSAEAAVWTLLQQQPAQL
LDPAYPDWHSLLIDAAKQVTDELGQQPGGLAARRWGKHNRTGIRHPLSAALPSWLARFID
MPDQPISGDSNMPHVAAPGFGASEHLDVAPGHEAEGILNMPGGQSDHPLSPYFGAGHADW
LQGRPTPLLPGATRHTLVLQPASR