Protein Info for LRK55_RS12655 in Rhodanobacter denitrificans MT42

Annotation: AI-2E family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 389 transmembrane" amino acids 12 to 42 (31 residues), see Phobius details amino acids 60 to 84 (25 residues), see Phobius details amino acids 128 to 146 (19 residues), see Phobius details amino acids 152 to 173 (22 residues), see Phobius details amino acids 214 to 242 (29 residues), see Phobius details amino acids 248 to 267 (20 residues), see Phobius details amino acids 274 to 294 (21 residues), see Phobius details amino acids 307 to 339 (33 residues), see Phobius details PF01594: AI-2E_transport" amino acids 11 to 341 (331 residues), 216.3 bits, see alignment E=3.3e-68

Best Hits

KEGG orthology group: None (inferred from 53% identity to psu:Psesu_1080)

Predicted SEED Role

"Putative permease often clustered with de novo purine synthesis" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (389 amino acids)

>LRK55_RS12655 AI-2E family transporter (Rhodanobacter denitrificans MT42)
MNHDKDISRRWQLFAITAVIVYLVWLLAPVLMPFAVAAMLAYLGDPLADRLERLGLNRMW
AATIVFVVIMVAVVGVLLLLIPLIARQVENLVSNLPRYGDWAQNTVWPWLQARLHLDPHT
FDSDRLLTAIKAHIGSIGGVATAVLGKVSRGGLGIAMWLTNLVLIPVVAFYLLRDWDRLV
AKVDGMLPRSIQPTIAHLASESDKILGAFVRGQLLVMLALGVFYGAGLGLVGLSVGLLIG
MVAGLLSFVPYLGFIIGFVAAIIAALVQYGDWTHVLLVCGVFAVGQLLEGYVLVPKLVGD
KIGLHPVAVIFAVLAGGYLFGFLGVLLALPAASVIMVLLRYLIERYRMSELYNEAGPEDP
VVAEVEVAAHRNGAVEATVDPPQDDRAEP