Protein Info for LRK55_RS12195 in Rhodanobacter denitrificans MT42

Annotation: acyl-CoA dehydrogenase C-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 596 PF12418: AcylCoA_DH_N" amino acids 4 to 35 (32 residues), 33 bits, see alignment (E = 1.5e-11) PF02771: Acyl-CoA_dh_N" amino acids 82 to 159 (78 residues), 32.8 bits, see alignment E=2.4e-11 PF02770: Acyl-CoA_dh_M" amino acids 165 to 279 (115 residues), 51.5 bits, see alignment E=2.8e-17 PF00441: Acyl-CoA_dh_1" amino acids 290 to 457 (168 residues), 73.3 bits, see alignment E=7.5e-24 PF08028: Acyl-CoA_dh_2" amino acids 305 to 450 (146 residues), 31.9 bits, see alignment E=4.5e-11 PF12806: Acyl-CoA_dh_C" amino acids 474 to 592 (119 residues), 100 bits, see alignment E=3.2e-32

Best Hits

KEGG orthology group: None (inferred from 61% identity to sml:Smlt3352)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.3.8.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (596 amino acids)

>LRK55_RS12195 acyl-CoA dehydrogenase C-terminal domain-containing protein (Rhodanobacter denitrificans MT42)
MTAYKAPLDDLRFALFDVLNAEPTLTALQGGEAHSRDLFDAVLEEAGRLSEQLLAPTNAP
ADAEGCRYDKASQTVTTPKGFKEAFKAFTEGGWTGLTNPEAYGGQALPGVLGTATTEIFQ
SGNLAWSLYPLLSEGATHAMEQHGEEWQRQRFMKPIVEGRWTGTMCLTEPQAGSDLGLLK
TRAEPGTADADGHPVYKLSGTKIFISAGEHDLAENIVHLVLARLPDAPEGSRGISMFIVP
KFKVNADGSLGARNTVAAGAIEHKMGIHACSTCVMNFDGAEGYLIGKPHKGLAAMFTMMN
AARLSVGVQGLALAERALQNSLNYARERLQSRALSGPKFPDKPADNLLVQPDVRRMLLTQ
RAFVEGSRALVLYTALQTDIEHRATDEAARQQAGELVAFLIPIAKGMTTELAQECTKEAL
QIYGGHGYIAENGMEQFVRDARIITLYEGTTGIQAADLLGRKILQLQGVGAKHFLQEISA
FCQQHSADTALRQLVGPLAVATKEWSELTLSLAQRVQANPEELGAAATDYLYYSGYVTLA
YLWARSVAAAEAGNQPAAFKQAKRDTAAFYFARILPRTLAHKAAIEAGIGSLPAID