Protein Info for LRK55_RS09515 in Rhodanobacter denitrificans MT42

Annotation: DEAD/DEAH box helicase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1017 PF04851: ResIII" amino acids 147 to 372 (226 residues), 37.1 bits, see alignment E=1.6e-13

Best Hits

KEGG orthology group: K01156, type III restriction enzyme [EC: 3.1.21.5] (inferred from 77% identity to dau:Daud_0199)

Predicted SEED Role

"Type III restriction-modification enzyme, helicase subunit"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.21.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1017 amino acids)

>LRK55_RS09515 DEAD/DEAH box helicase family protein (Rhodanobacter denitrificans MT42)
MENQFFERPILNSPYDYPARHWELDESGQPTQQVIDSRRGADFVTPIPRPRKRNGGGEQG
DLALGDTGLSTDAQRYHSALINGVRQQVDRWRLIPDPAQWHVTPETARLLQHWRHHKFGG
LRPFFCQVEAAETAIWLVEVAPQLGKAAQNILDHLTNANHDANPELMRLALKLATGAGKT
TVMAMLIAWQTVNAVRHPNSRRFTRGFLVVAPGITIRDRLRVLQPNDPYSYYKSRELVPA
DMMGDLERAKIVITNYHAFKLRERLELSKGGRRLLQGKGGAALDTQETEGQMIQRVMPDL
MGMKNILVINDEAHHCYREKPGTAADLDELKGDDKEEAKNNNEAARVWISGLEAVNRQLG
VNRVIDLSATPFFLSGSGYAEGTLFPWTMSDFSLMDAIECGIVKLPRVPVADNVPGSEMP
KFRELWKHIGKKMPKKGRGKSKALDPLALPVELQTALEALYGHYAETYKLWQQAGIRVPP
CFIVVCQNTAISKLVYDYISGFVRENDDGAGEFVNGRFELFRNYDEHGNPIPRPRTLLID
SEQLESGEALDKGFRDMAADEIERFRREIIERSNDPRAADAISEQDLLREVMNTVGKADR
LGESIRCVVSVAMLTEGWDASTVTHVLGVRAFGTQLLCEQVIGRALRRQSYELNAEGLFD
VEYADVLGIPFDFTAKPVVAPPQKPRETIHVKAVRPERDALEIRFPRVLGYRVELPEDRL
TAEFNDESTLTLTPDLVGPSITRNAGIIGEGVDLSLKHLGDMRMSTLLFHLTQRLLYTKW
RDPNEDARLNLFGQLKRITRQWLDTRLVCKGGTYPAQLMYQELADMACNKITTAITRAEL
GRRPIKAMLDPYNPVGSTRHVNFSTSRTERWETDARRCHINWAILDSDWEGEFCRVAEAH
PRVRAYVKNHNLGLEVPYRFGSLHRIYVPDYIVQVDDGHGDDDPLNLIVEIKGYRREDAI
EKKATMDTYWVPGVNHLGSHGRWAFAEFTDVYAMQEDFSKKIEAEFDKMIANASKGA