Protein Info for LRK55_RS07550 in Rhodanobacter denitrificans MT42

Annotation: efflux RND transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1056 signal peptide" amino acids 12 to 16 (5 residues), see Phobius details amino acids 33 to 36 (4 residues), see Phobius details transmembrane" amino acids 17 to 32 (16 residues), see Phobius details amino acids 334 to 353 (20 residues), see Phobius details amino acids 360 to 381 (22 residues), see Phobius details amino acids 387 to 411 (25 residues), see Phobius details amino acids 431 to 451 (21 residues), see Phobius details amino acids 463 to 490 (28 residues), see Phobius details amino acids 536 to 556 (21 residues), see Phobius details amino acids 870 to 889 (20 residues), see Phobius details amino acids 896 to 915 (20 residues), see Phobius details amino acids 921 to 947 (27 residues), see Phobius details amino acids 971 to 993 (23 residues), see Phobius details amino acids 1000 to 1026 (27 residues), see Phobius details PF00873: ACR_tran" amino acids 7 to 1024 (1018 residues), 923.6 bits, see alignment E=1.4e-281

Best Hits

Predicted SEED Role

"RND multidrug efflux transporter; Acriflavin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1056 amino acids)

>LRK55_RS07550 efflux RND transporter permease subunit (Rhodanobacter denitrificans MT42)
MNIFAPLIRRPVGTSLLALGLMLAGLWAYLLLGVAALPSLDFPGVYVVASQPGASAQTMA
NTVLAPLERHLGRIPGVDEMYGNASEGQASVMVRFTFDRTADSAARDVQAAINAAAVDLP
SGMPSPPQYFKFDTAQIPILFLTLTSTGLPQDQLFDLADTMLKPAVAQIDGVAQVQVFGG
TPHAVRIELDNGALAAKGLTTNDVANALRAANVTSPQGTLSDGRTQMTVSASDSLQTPTE
FARLLISAKNGTPVRLSDVAKVYSGQQDEYQAAWFNDARAVGLQISKRPEANAVATVEAI
RARLPQLRASLPQNVTMTPVFDLTQTTKSALHEVQVALLISIAMVVLVMLVFLRRLRPTL
IATLSVPLSLAGAFVVMWALGYTLNTLSLVALVLCIGFVVDDAIVVIENIVRHMERGEPP
MQAALTGVREIGFTVISITLSLVAVFAPLLFGNNMLIMLLREFSVTLTAAVVISALVSLT
LTPALCAWMLTHEPERSRPPGRIEQAVENFDRKLLHVYQRALDWAMHHRRIMRWQPLTLL
VLTFVLGFAVAKTAGGTFMPDEDTGQLQVDISADANISPAELTARALAVAKIMQADPAVL
DQLTMLGRDGGGGGAVGNNAQMFVDLKPRGSGPGQRREGIKQVVERLSKQYDKLANVKVS
VSAAQFLGGGGSGDKGGQYEFQLVSSNGGDLQPWTLKMVRQLRGMQQFRDVSSSFDQVGK
QQLLRIDREAAARLHVGVGTIDSALYNAFGQRQVSQIYSDINQYAVVLSTGAAERVSPES
LLDVRVRNEQGRMIPLSALATIEPNMSPLRVRHHNQLEAATISYNLAKDVTQDVGVKLVE
QAAYAARLPAGMRVDFTGANQRLKQAQSNGMVLLLGSILAMYIVLGILYESLGHPLTILS
TLPAAGAGAFLAMLVTQTQISMMAIIAILMLIGIVKKNAILMVDFALVAERERGLPAPEA
IREAALVRFRPITMTTLVAMGAALPLAIGFGIGSEMRQPLGIAIVGGLLVSQLLTLLSTP
AIYLWNYDRKIRKAARRERKAEKKRLKTLGKVQTAS