Protein Info for LRK55_RS06850 in Rhodanobacter denitrificans MT42

Annotation: cytochrome c oxidase subunit 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00510: COX3
  • amino acids 8 to 118 (111 residues), 51.3 bits, E=7.6e-18
  • amino acids 153 to 294 (142 residues), 155 bits, E=1.8e-49

Best Hits

KEGG orthology group: K02276, cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 66% identity to xcb:XC_3901)

Predicted SEED Role

"Cytochrome c oxidase polypeptide III (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

• aerobic respiration I (cytochrome c) (3/4 steps found)
• arsenite to oxygen electron transfer (1/2 steps found)
• aerobic respiration II (cytochrome c) (yeast) (2/4 steps found)
• arsenite to oxygen electron transfer (via azurin) (1/3 steps found)
• Fe(II) oxidation (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Protein Sequence (295 amino acids)

>LRK55_RS06850 cytochrome c oxidase subunit 3 (Rhodanobacter denitrificans MT42)
MGQQHDAYFVPTKSYWPFVAAVVMFTTVFGAAHWLNADPGESGFGKSVLTIGVLGVLGMF
FGWFRSVINESLAGSYNHQVDTSFRMGMMWFIFSEVMFFGAFFGALFYVRMFSVPWLGGH
GHGVLTHEFLWSDYTAAWGANGGNGPEQAGGAFRTVPAWGLPLLNTLILLTSSVTVTIAH
HALRAGHRGKILLFLGLTVLLGATFLYFQAHEYIEAYKELNLTLHSGVYGSTFFLLTGFH
GLHVTLGTIMLAVIWLRVLKGHFNKEHHFGFEAVAWYWHFVDVVWLGLFMFVYIL