Protein Info for LRK55_RS04325 in Rhodanobacter denitrificans MT42

Annotation: aldo/keto reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF00248: Aldo_ket_red" amino acids 16 to 321 (306 residues), 233 bits, see alignment E=2.1e-73

Best Hits

Swiss-Prot: 51% identical to KCAB_ORYSJ: Probable voltage-gated potassium channel subunit beta (KOB1) from Oryza sativa subsp. japonica

KEGG orthology group: None (inferred from 71% identity to xca:xccb100_3587)

Predicted SEED Role

"Voltage-gated potassium channel beta subunit"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (324 amino acids)

>LRK55_RS04325 aldo/keto reductase (Rhodanobacter denitrificans MT42)
MLYRRLGTSGLQLSVLSFGAWVTFGRQVGRDEARDLLALAHDRGVNYFDNAETYNNGVAE
QLMGDVLADLRFPRDSYCVSSKVFFGAVDKPLPTQRGLSRKHVMEACHQALQRLRVDYLD
LYFCHRPDPDTPIAETVAAMDTLVRQGKVLYWGTSEWPAEAIHEAHRVARENHLYAPVME
QPQYNLLHRERVELEYAPLYEAYGMGTTIWSPLASGLLSGKYNDGVPADSRLAQPDYEWL
RESVLGHGDERLGKVRALQPIAAELGTSLAQLAIAWCLLNPHVSTVMLGASKREQLAQNL
DALALLPRLDAAVAQRIRQVVEAG