Protein Info for LRK55_RS03815 in Rhodanobacter denitrificans MT42

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 751 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF07715: Plug" amino acids 45 to 155 (111 residues), 45 bits, see alignment E=2.1e-15 PF00593: TonB_dep_Rec" amino acids 334 to 727 (394 residues), 171.6 bits, see alignment E=8.6e-54 PF14905: OMP_b-brl_3" amino acids 404 to 733 (330 residues), 60.1 bits, see alignment E=3.4e-20

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 46% identity to bvi:Bcep1808_0930)

Predicted SEED Role

"Outer membrane receptor proteins, mostly Fe transport" in subsystem Hemin transport system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (751 amino acids)

>LRK55_RS03815 TonB-dependent receptor (Rhodanobacter denitrificans MT42)
MNTLPLGLCAVALAVSASSLLAADEPAPATTLAPISVHASDTMVMETPSVQVRLKRQKLQ
QQNLTESADALKYAPNMMVRKRYIGDPNAVISGRNAGTLQSARSLVYADGLLLSNLMTNG
WDGAPRWGMVAPEEIGAVDILYGPYSALYPGNSLGSTVLVHTVLPQQFTASVSTQFFSQD
YRDAYGAGGHYNGHQAAATLGDKQGRFSWLLEFSRLDNHGQPMQYATAKAGGNAAAALPV
SGAVPDRNPNGSPRLVYGANSIEHTVQDQAKLKVGVDLTDHVAVLFTVGWWHNRAEDRTR
SLIRDAAGHPVTGGAISAAGQTWTLPASGLAPSSASDTHLLYGVELNGHLDNGWRWTAVA
SHYDFLRSQAATANLAEPGVPTGGPGTIADKAGSGWDTLDLRSSGPLGERHMLYAGAHGD
RYVLDSRVRSASDWRGDADGAQVSAFAGRTQTRALYLQDVWSFADAWALTVGGRLEQWRA
YGGLRANAVNAVHYADRRRTDFSPKAALSWDLADGWELRLAHGKAVRYPTVTELFQGSLS
ANAIVNNNPALKPETDESTDLTLTRHLAHGHWRVSLYQDRIADSLYSQTDITVTPTVTSV
QNIDRMRSRGIEGEINLTNLWLDGLDLQASLAFNHAKTLEDRQYPLANGKTFPRIPKVRA
SVFADYRFAPQWDASLGIRHSGRQYGTLDNSDYVDGYGAVSRFTVADAKLRWKFAPGWTA
ALGVDNLTNEQYWVYHPYAGRTWFGELHWEL