Protein Info for LRK55_RS03635 in Rhodanobacter denitrificans MT42

Annotation: pilin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 146 transmembrane" amino acids 7 to 31 (25 residues), see Phobius details PF07963: N_methyl" amino acids 3 to 28 (26 residues), 40.9 bits, see alignment 1e-14 TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 5 to 28 (24 residues), 38.6 bits, see alignment 2.9e-14 PF00114: Pilin" amino acids 37 to 145 (109 residues), 84.5 bits, see alignment E=1e-27

Best Hits

Swiss-Prot: 50% identical to ECPC_EIKCO: Fimbrial protein EcpC (ecpC) from Eikenella corrodens

KEGG orthology group: K02650, type IV pilus assembly protein PilA (inferred from 57% identity to tin:Tint_0572)

Predicted SEED Role

"Type IV pilin PilA" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (146 amino acids)

>LRK55_RS03635 pilin (Rhodanobacter denitrificans MT42)
MKKMQKGFTLIELMIVVAIIAILAAIAIPAYQDYLIRTQVSEGAVLTDGAKTAVAEFYSN
RGDLTNAKNASIGLAQAASIKGQYVSQVDVAGGIITASFAGPKANKAISTGPKTFVLSPV
TSAGSISWVCTRSTVDQKYLPTSCRK