Protein Info for LRK54_RS15675 in Rhodanobacter denitrificans FW104-10B01

Annotation: cytochrome oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 182 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 48 to 68 (21 residues), see Phobius details PF00116: COX2" amino acids 105 to 170 (66 residues), 30.8 bits, see alignment E=1.2e-11

Best Hits

Predicted SEED Role

"Cytochrome c oxidase (B(O/a)3-type) chain II (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (182 amino acids)

>LRK54_RS15675 cytochrome oxidase (Rhodanobacter denitrificans FW104-10B01)
MVLQNVIWAITLTGMGLVALGFIYAIAQAGKPADTAEAERAHRTSISLRRALFAALLLLG
IGIAWASLRPFPIPPQHQPLEAAQVVEVVGHQWTWDVSQTHLRAGEPVEFRVTASDVNHG
FAIYAPDGRIVIQTQAMPGFTNKILYTFHTPGTYKIMCLEYCGVAHNGMTAEFDVAARED
KS