Protein Info for LRK54_RS14655 in Rhodanobacter denitrificans FW104-10B01
Annotation: peptide-methionine (R)-S-oxide reductase MsrB
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K07305, peptide-methionine (R)-S-oxide reductase [EC: 1.8.4.12] (inferred from 50% identity to acm:AciX9_2804)Predicted SEED Role
"Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12)" (EC 1.8.4.12)
Isozymes
Compare fitness of predicted isozymes for: 1.8.4.12
Use Curated BLAST to search for 1.8.4.12
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (200 amino acids)
>LRK54_RS14655 peptide-methionine (R)-S-oxide reductase MsrB (Rhodanobacter denitrificans FW104-10B01) MPRLDETLAMDRRRFLRAALGGGALLAVGGGLLLPRLHAAANAPVGAPGEVLLEIFDDAG HDLGARKVAKLVLSDAQWRQRLSPAAYEVMRHEDTERAFSGEHERPAVPGLFRCVACATA LYDAATEFDSGTGWPSFWQPIAARNVIERSDHLFGMQRTAISCAGCDSHLGHVFDDGPRP TGLRYCMNSVALRFVPHAAA