Protein Info for LRK54_RS12390 in Rhodanobacter denitrificans FW104-10B01

Annotation: low-specificity L-threonine aldolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 339 PF01212: Beta_elim_lyase" amino acids 5 to 285 (281 residues), 345.7 bits, see alignment E=2.2e-107 PF00155: Aminotran_1_2" amino acids 13 to 305 (293 residues), 25.8 bits, see alignment E=6e-10

Best Hits

Swiss-Prot: 57% identical to LTAA_AERJA: L-allo-threonine aldolase (ltaA) from Aeromonas jandaei

KEGG orthology group: K01620, threonine aldolase [EC: 4.1.2.5] (inferred from 64% identity to bbr:BB3723)

MetaCyc: 57% identical to L-allo-threonine aldolase subunit (Aeromonas jandaei)
LTAA-RXN [EC: 4.1.2.48, 4.1.2.49]

Predicted SEED Role

"Low-specificity L-threonine aldolase (EC 4.1.2.48)" (EC 4.1.2.48)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.2.48 or 4.1.2.49 or 4.1.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (339 amino acids)

>LRK54_RS12390 low-specificity L-threonine aldolase (Rhodanobacter denitrificans FW104-10B01)
MEWVDLRSDTVTRPTAAMRAAMLGAEVGDDVYGEDPTVNALQQRLADELGFDAGLFVPSG
TQSNLLALMSHCERGDEYLVGADAHTYKFEGGGAAVLGSIQPQPIVQAADGSLPLERIEA
AIKPVDPHFARTRVLALENTWHGRTLPLDYLQAAHDAARAHGLGLHLDGARLFNAAIACN
VPAREIARHFDTVSVCLSKGLGAPVGSVLLGSHALIDKARRWRKVAGGGWRQAGMLAAAG
QYALDHHVARLADDHRRAAYLAGRLREIAGVDLLGQYTNMVFIDVPAGRLRELDVHLRDA
GIRISIGYLPTLRLVTHLDVDDAGIERTAAAFAEFFGRG