Protein Info for LRK54_RS10495 in Rhodanobacter denitrificans FW104-10B01

Annotation: type I restriction endonuclease subunit R

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1078 transmembrane" amino acids 652 to 673 (22 residues), see Phobius details PF04313: HSDR_N" amino acids 5 to 215 (211 residues), 144.5 bits, see alignment E=8e-46 TIGR00348: type I site-specific deoxyribonuclease, HsdR family" amino acids 8 to 726 (719 residues), 478.4 bits, see alignment E=2e-147 PF18766: SWI2_SNF2" amino acids 277 to 502 (226 residues), 235.7 bits, see alignment E=1e-73 PF04851: ResIII" amino acids 282 to 438 (157 residues), 67.4 bits, see alignment E=3e-22 PF11867: T1RH-like_C" amino acids 731 to 1066 (336 residues), 89.5 bits, see alignment E=5.7e-29

Best Hits

KEGG orthology group: K01153, type I restriction enzyme, R subunit [EC: 3.1.21.3] (inferred from 70% identity to slt:Slit_2435)

Predicted SEED Role

"Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1078 amino acids)

>LRK54_RS10495 type I restriction endonuclease subunit R (Rhodanobacter denitrificans FW104-10B01)
MPNPITEDQIEQALLDRLTASSGWSVLNCHTAERDQLADGSGRADKSEVILLDRLRAAAR
RLNPELPGSVLDEALERLCDRRPAMTAVMANREVYDLLCHGIAVEFDDAQGRRQYERLRV
IDFRDTARNDFLAVSQLWIKGERGGYRRPDVLLYVNGLPLVFIELKNSNVALKSAYTDNL
TTYRHEIPQLFLCNAFCVLSNALDTRVGSLTAEWEHFFTWLRPDDEKEKIDREQIRADGT
SLERVIDGLFVPARLLDYVENFILFHKQTQKIIAQNHQFIGVNRALERFDRRAELDGKLG
VFWHTQGSGKSFSMIFYVRKIFRRTPGNFTFVVVTDREDLDGQIYRNFLNTETVSQAAAA
QPKNSAEMRQFLGQNKRLVFTLIQKFRYAAGAAYPLLSDRADIVVIIDEAHRTQYASLAE
NMRAGLPNANYLAFTGTPLLGRERKTATWFGGYVSEYNFQQSMDDGATVPLFYCKRVPEV
LIQNEDLSEEFYEILEDENLDEAQQAKLEQRFAREVEVIKRDDRLEAIARDIVSHFPRRG
YLGKAMVISLDKFTALRMHDKVQALWKDEVKALVGRIAGSADELEKARLKKRLEYMRGVE
MAVIVSEEAGEEEKFAKQKLDIKLHRSRMSRLDANGHDIEYNFKDPGDSLQLVFVCAMWL
TGFDAPTVSTLYLDKPMKDHTLMQTIARANRVTSWLISGVPKRNGEIVDYYNVFRNMKRA
LRDYAQGDSDEERPPVQPKDELFVLLDEAIAQGRTFCAERGVELDNVLAQANVFEKVGEF
GRFADTLLGNDEWRRSFNVYENSISALYEASKPEILGRPVTRQVAVFQYLRGVIDSAIGE
ADIDDVARRVGELLDQSVVVDRQSGSWQADRASPVYQIVQKGRVWDLSRIDFDKLRAEFT
ATEYKNIEIADLRAFIARKLEQMLQANATRADFAQRLQQIIDSYNAGGSSNEQYFEELLK
FTRDLKAEDERHLREGLTEDELELYDLLLQDGLSKDETQKVKLAARHLLHRLLEESPKVL
VQDWFKDRQTQEAVRNAVVTVLDADLPSSYDRALFKQKCDRVFEVMMEYASRGQKWAA