Protein Info for LRK54_RS09450 in Rhodanobacter denitrificans FW104-10B01

Annotation: Atxe2 family lasso peptide isopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 728 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details PF07676: PD40" amino acids 63 to 80 (18 residues), 12.7 bits, see alignment (E = 1e-05) amino acids 128 to 147 (20 residues), 14.9 bits, see alignment (E = 2.1e-06) PF00326: Peptidase_S9" amino acids 536 to 692 (157 residues), 33.6 bits, see alignment E=2.8e-12

Best Hits

Predicted SEED Role

"acylaminoacyl-peptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (728 amino acids)

>LRK54_RS09450 Atxe2 family lasso peptide isopeptidase (Rhodanobacter denitrificans FW104-10B01)
MKLLFQPLLWAAVTARLRPDPSTRKRHTRWVPAFALVLGVAVAGPSPAETISPRRLLEVT
DLGNPVISPDGRYVAFRAEQASIERNTYDTTWYVQGLDGQSPPRRVSDGGVPLREYVSGL
VLPSPAVWSPDGRWIYYRARLDGRVSVWRAAADGSGARAMTSDPADVRDFALSGDGQTLR
YSVGATREEVIAAEESEYDHGIHVDDTVVIAAGLFRSSKLDGRPTTQRFLGDWFSTGPLL
AKVPDRWKAVDLTAMTTHDLSASEPPAHTLIAADLSPDLPAAPTKIALNSGDGRIAVLMP
GRTEKGLLLSRDVELAMLPDRHASRPIRCMAELCRHRHISDIQWRSGSDEILFTATDYDQ
GRAQSIYGWNVSTGTVRPIVISNGLVSGSQRYWDIPCALSVDTLVCVAAEADRPPRLEAI
DVASGHKRILFQPNMGLEADIAATVPARLIRWKDKQGREFTGQLFEAHGARAGHPPPLFV
TFYNCYGFLRGGLGDEWPLATLAEQGISALCINAIPEFRIDFVARHDQGRAAVESVVKPL
SAEGRVDRARVGMGGLSYGSEVTLWTLAHSDVVSAASVSSMSVTPTYYLFNSLRGAFRSN
LLKLWQLGAPDETPERWREISPVYQLGRIKAPILFQMIEQEYRMALDYALPLVRRHQADV
YVFPDEPHIKFQPRHKLAVYERNVDWFRFWLQGYEDPSLVKKQQYAHWREMRDAVSARPA
RSGAHSGG