Protein Info for LRK54_RS07075 in Rhodanobacter denitrificans FW104-10B01
Annotation: magnesium-translocating P-type ATPase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 55% identical to ATMA_ECO57: Magnesium-transporting ATPase, P-type 1 (mgtA) from Escherichia coli O157:H7
KEGG orthology group: K01531, Mg2+-importing ATPase [EC: 3.6.3.2] (inferred from 62% identity to azc:AZC_0192)Predicted SEED Role
"Mg(2+) transport ATPase, P-type (EC 3.6.3.2)" (EC 3.6.3.2)
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.2
Use Curated BLAST to search for 3.6.3.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (884 amino acids)
>LRK54_RS07075 magnesium-translocating P-type ATPase (Rhodanobacter denitrificans FW104-10B01) MIKQSIQGALPRAADRGASAPLHVAVAQEAFRANSELLASLETTPAGLDEEQIEARLHRD GINEVSYEKPPHWSRQLLRAFKNPFIIVLLVLAVVQMFATPDDLSGPIIIAAMVGISVLL SFTQEYRSSKAAEKLKAMVRNTATVTRRASDGHSERIEVPVGELVAGDIVHLAAGDMVPA DLRLLHAKDLFISQAILTGESLPVEKAAPGAHGAAEADHANPLDLPTICYMGTNVVSGTA TAVAVATGPRSYLGSLAHSIVGQRVQTSFDRGVNSVSWLLIRFMAVMVPVVFLINGFDKH DWLQAFMFALSVAVGLTPEMLPLIVTANLAKGALAMSRRKVVVKRLNAIQNFGAMDVLCT DKTGTLTLDKIVLERHLDLHGEESDEALEYGYLNSRFQTGLKNLMDKAVLAHRDLEPAAA HYRIVDEIPFDFQRRRMSVVLGNGDGHDLIVCKGAVEEMLSICTWAKTGDQIVPMTDAQR DEIKEMTRGLNEDGLRVLVVAVKQQPPAGRPYGVADESGLTAVGCLAFLDPPKDSAATAI AALHHHGVQVKVITGDNEAVTRKICREVGLDVEHSAQGRQIEPLDDAALDELVKRTTVFA KMSPLQKARVVKSLQRQGHTVGFLGDGINDAPALREADVGISVDTATDIAKESADIILLE KNLMVLEEGVIEGRITFGNIIKYIKMTASSNFGNMFSVLVASAFLPFLPMLPLQILVLNL LYDISQLSIPFDRMDDEYLRKPRKWDASDIGRFMVWIGPVSSIFDITTFLLLWHVFGANS MAHQPFFQSGWFIESLLTQTLIVHMIRTRRIPFLQSIASAPVLALTTAVILIGLFVPFTG LGAKIGMVALPPAFFGWVALTVLTYGVLTQLMKLVYIRRYGRWL