Protein Info for LRK54_RS02205 in Rhodanobacter denitrificans FW104-10B01

Annotation: prepilin-type N-terminal cleavage/methylation domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 transmembrane" amino acids 21 to 50 (30 residues), see Phobius details PF07963: N_methyl" amino acids 22 to 44 (23 residues), 27.1 bits, see alignment (E = 1.1e-10) TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 23 to 44 (22 residues), 19 bits, see alignment (E = 4.8e-08)

Best Hits

Predicted SEED Role

"Type IV fimbrial biogenesis protein PilW" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (350 amino acids)

>LRK54_RS02205 prepilin-type N-terminal cleavage/methylation domain-containing protein (Rhodanobacter denitrificans FW104-10B01)
MSKRFLIRRGAGRGKVWSALPSAGFTLIELMVAMLLGLIVIGGVVSVFLANQRTYRTNQA
LGDVQDGSRLAFELMARDIREAGLTGCNNNGRMSNVLNNKSTAWWADWGNAVHGYGAGTA
TADPALTVGTAATNQVSGTDSLQLLGAADSGLSVAATPSSTAANFKLNDTTSDIVKGDVI
IVCDPDHAAIVQVTNYNSSNVTLDHNNGSNPLPGNCSKGLGFPTTCTANGNGYTFGPNSQ
IFKLGAVDWYIGYNPLGGKSLYRVNVVTTAGTPTPTTQEMVRDVTGMAISYHQAGIASFV
DAKTVAANWGAVDAVQVQLTVESVDKRAGTDTKPITRQFTATTTVRNRVQ