Protein Info for LRK54_RS00375 in Rhodanobacter denitrificans FW104-10B01

Annotation: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01066: CDP-OH_P_transf
  • amino acids 4 to 175 (172 residues), 127.7 bits, E=2.7e-41
• TIGR00560: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
  • amino acids 4 to 188 (185 residues), 170.4 bits, E=2.8e-54

Best Hits

Swiss-Prot: 54% identical to PGSA_PECAS: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (pgsA) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K00995, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [EC: 2.7.8.5] (inferred from 53% identity to xfm:Xfasm12_1317)

Predicted SEED Role

"CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.8.5)

MetaCyc Pathways

• phosphatidylglycerol biosynthesis I (6/6 steps found)
• phosphatidylglycerol biosynthesis II (6/6 steps found)
• superpathway of phospholipid biosynthesis III (E. coli) (10/12 steps found)
• cardiolipin biosynthesis II (3/3 steps found)
• cardiolipin biosynthesis I (2/3 steps found)
• cardiolipin biosynthesis III (2/3 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (9/13 steps found)
• type I lipoteichoic acid biosynthesis (S. aureus) (6/17 steps found)
• superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.5

Protein Sequence (200 amino acids)

>LRK54_RS00375 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Rhodanobacter denitrificans FW104-10B01)
MHINLPTWLTLFRVALLPVMVVVFYLPFAGHNITAAVVFVLAAVTDWLDGYLARRMNLTS
AFGAFLDPVADKLMVAVTLFLLVESHRGGWPGVLMAVTAAVIVGREISVSALREWMAEIG
MRATVKVAFIGKLKTVMQMVALVVLIVQHEKAAEALRLYHIGEALLVIAGVLTIWSGLHY
LRAAWPSLSADGASSKRAAE