Protein Info for IAI47_01235 in Pantoea sp. MT58

Annotation: potassium-transporting ATPase subunit KdpA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 562 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 60 to 81 (22 residues), see Phobius details amino acids 94 to 113 (20 residues), see Phobius details amino acids 129 to 150 (22 residues), see Phobius details amino acids 171 to 191 (21 residues), see Phobius details amino acids 248 to 269 (22 residues), see Phobius details amino acids 280 to 299 (20 residues), see Phobius details amino acids 327 to 347 (21 residues), see Phobius details amino acids 354 to 396 (43 residues), see Phobius details amino acids 416 to 435 (20 residues), see Phobius details amino acids 479 to 504 (26 residues), see Phobius details amino acids 524 to 547 (24 residues), see Phobius details TIGR00680: K+-transporting ATPase, A subunit" amino acids 1 to 556 (556 residues), 865.4 bits, see alignment E=9.1e-265 PF03814: KdpA" amino acids 11 to 554 (544 residues), 802.1 bits, see alignment E=1e-245

Best Hits

Swiss-Prot: 81% identical to KDPA_ERWT9: Potassium-transporting ATPase potassium-binding subunit (kdpA) from Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)

KEGG orthology group: K01546, K+-transporting ATPase ATPase A chain [EC: 3.6.3.12] (inferred from 98% identity to pva:Pvag_3068)

MetaCyc: 77% identical to K+ transporting P-type ATPase subunit KdpA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-2 [EC: 7.2.2.6]

Predicted SEED Role

"Potassium-transporting ATPase A chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12 or 7.2.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (562 amino acids)

>IAI47_01235 potassium-transporting ATPase subunit KdpA (Pantoea sp. MT58)
MAANAFLLIAFYLVLLMVLAQPLGRGLASLVADKPVFARLETPLWRLLGAQASDMRWPHY
LLAILLFNALGFVVLLSILLLQGSLPLNPQQLPGLSWHLALNTAVSFVTNTNWQAYSGES
TLSYFSQMVGLTVQNFLSAATGIAVAFALIRGFANRSSATLGNAWRDLTRITLYVLLPIS
LLMALFFVSQGSIQNFSPYHSFSTLEGVQQTLSMGPVASQEAIKMLGTNGGGFFNANSSH
PFENPTVLTNLVQMLSIFLIPAALCFAFGESVRDRRQGHMLLWAMTLMFVAAVAVVMWAE
LQGNPHFLQLGADSAINMEGKETRFGILNSSLFAVITTAASCGAVNAMHDSFTALGGMVP
MWLMQLGEVVFGGVGAGLYGMLLFVLLAVFIAGLMIGRTPEFLGKKVDVWEMKMTALAIL
VTPALVLIGTALAMMTDAGRSAMANPGIHGFSEVLYAVSSAANNNGSAFAGLSVNTPFWN
LLLAVCMLLGRFGIIIPVMAIAGAMAVKKVQPVGNGTLPTHGPLFIALLIGTVLLVGALT
FIPALALGPVAEHLQLVQGQSS