Protein Info for HSERO_RS23925 in Herbaspirillum seropedicae SmR1

Annotation: multidrug ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 618 transmembrane" amino acids 38 to 62 (25 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 181 to 202 (22 residues), see Phobius details amino acids 269 to 290 (22 residues), see Phobius details amino acids 296 to 317 (22 residues), see Phobius details PF00664: ABC_membrane" amino acids 42 to 307 (266 residues), 40.4 bits, see alignment E=3e-14 PF00005: ABC_tran" amino acids 379 to 532 (154 residues), 112.5 bits, see alignment E=2.6e-36

Best Hits

Swiss-Prot: 65% identical to Y1051_HAEIN: Uncharacterized ABC transporter ATP-binding protein HI_1051 (HI_1051) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 100% identity to hse:Hsero_4782)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IZ39 at UniProt or InterPro

Protein Sequence (618 amino acids)

>HSERO_RS23925 multidrug ABC transporter ATP-binding protein (Herbaspirillum seropedicae SmR1)
MFSWFEKLVQPYPEHHPLPPPRGFMRFIWFCTKGVRPYIAAMTLMTAIIGVFEALLFAAL
GRIVDWLAKIAPSQLWSQEGHTLTWLVLILAASPLLIALQTMYKHQTLAGNFPMLLRWNF
HRLMLSQSMSFYQNEFAGRVATKVMQTALAVRDFCMIVGDILVFITIYFATLIGVVGSFD
IWMLAPFFIWLAAFAVALRYFVPRLSAVARNQADARSLMTGRITDAYTNIATVKLFSHAG
READYARSAMREFLVTVNQQMRLVSGFEVVNHLLNMVLIIGATGVSLYLWTQGKVGVGAV
AASTAMALRLNGIAHWVMWEMSSLFEHVGTVQDGINTLARAHDVKDAPDAQPLKVSQGEL
RFEGVSFSYGGAAPRPVVDKLDLVIRPGEKIGLVGRSGAGKSTIVNLLLRFYDIEGGRIT
IDGQDIAHVTQDSLRAQIGMVTQDTSLLHRSVRENITYGRPDASDAEMTHAAERAEAHDF
IGTLADAKGRTGYDAHVGERGVKLSGGQRQRIAIARVMLKDAPILLLDEATSALDSEVEA
AIQTSLYKLMEGKTVVAIAHRLSTIAAMDRLIVLDQGRIVEQGSHAELLAANGLYARLWS
HQSGGFLGEEEEDAAVMA