Protein Info for HSERO_RS23730 in Herbaspirillum seropedicae SmR1

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 475 transmembrane" amino acids 33 to 54 (22 residues), see Phobius details amino acids 67 to 88 (22 residues), see Phobius details amino acids 98 to 119 (22 residues), see Phobius details amino acids 126 to 148 (23 residues), see Phobius details amino acids 159 to 180 (22 residues), see Phobius details amino acids 186 to 206 (21 residues), see Phobius details amino acids 218 to 236 (19 residues), see Phobius details amino acids 242 to 262 (21 residues), see Phobius details amino acids 283 to 307 (25 residues), see Phobius details amino acids 319 to 337 (19 residues), see Phobius details amino acids 346 to 367 (22 residues), see Phobius details amino acids 376 to 395 (20 residues), see Phobius details amino acids 413 to 436 (24 residues), see Phobius details amino acids 443 to 465 (23 residues), see Phobius details PF07690: MFS_1" amino acids 37 to 426 (390 residues), 172.9 bits, see alignment E=9e-55 PF00083: Sugar_tr" amino acids 65 to 202 (138 residues), 28 bits, see alignment E=1.1e-10

Best Hits

Swiss-Prot: 52% identical to YEBQ_ECOLI: Uncharacterized transporter YebQ (yebQ) from Escherichia coli (strain K12)

KEGG orthology group: K08169, MFS transporter, DHA2 family, multidrug resistance protein (inferred from 100% identity to hse:Hsero_4743)

Predicted SEED Role

"putative transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IY82 at UniProt or InterPro

Protein Sequence (475 amino acids)

>HSERO_RS23730 MFS transporter (Herbaspirillum seropedicae SmR1)
MSSQPTAPGTAAPSPHIVIAGEGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALD
LQTTPAASVWIVTAYQLAMMVALLPLAALGEIIGYRRIYIWGLVLFTAASLLCAVAWSLP
TLVMARFLQGLGGAGIMSVNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILA
IAPWPWLFAVNVPLGVLAVVLAVPSLPHTSLARHAFDLRSALLNAAAFGLLILAIGEGAH
QAQASVVGLELAAAILCGLFLLKRELSHPAPMLPVDLFRHPMFSLSAVTAVCSFAAQGLA
FVSLPFFFHHDLGRSQVEIGLLMTPWPVAVAIMAPIAGRMSDRYPVGMLGGVGLALLCAG
LLSMTFMPASPSVWEISWRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLL
GQSVGAALVALCFNLSQTQGSRLALGFGAAFAGAACIASFLRLLTRNPYAPPPKK