Protein Info for HSERO_RS23560 in Herbaspirillum seropedicae SmR1

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 52 to 71 (20 residues), see Phobius details amino acids 83 to 101 (19 residues), see Phobius details amino acids 107 to 128 (22 residues), see Phobius details amino acids 140 to 162 (23 residues), see Phobius details amino acids 164 to 165 (2 residues), see Phobius details amino acids 168 to 186 (19 residues), see Phobius details amino acids 220 to 243 (24 residues), see Phobius details amino acids 255 to 278 (24 residues), see Phobius details amino acids 290 to 309 (20 residues), see Phobius details amino acids 315 to 337 (23 residues), see Phobius details amino acids 348 to 370 (23 residues), see Phobius details amino acids 376 to 396 (21 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 17 to 395 (379 residues), 323 bits, see alignment E=1.8e-100 PF07690: MFS_1" amino acids 22 to 363 (342 residues), 150.4 bits, see alignment E=6.6e-48 PF00083: Sugar_tr" amino acids 50 to 116 (67 residues), 48.2 bits, see alignment E=8e-17

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 100% identity to hse:Hsero_4709)

Predicted SEED Role

"Multidrug resistance transporter, Bcr/CflA family" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IY53 at UniProt or InterPro

Protein Sequence (406 amino acids)

>HSERO_RS23560 MFS transporter (Herbaspirillum seropedicae SmR1)
MQNNDTSLSTGKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFL
IGVAVGQMFYGPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAG
MVIPRAMVRDRMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGL
LCILGTRKYLTETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAG
GPFVVIELHGVKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLT
VSLLVLVGLETLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMG
VLSGVAMSLWHDGTALPLVSVMAVCGVTALLVYHFAAKHAPAVSPQ