Protein Info for HSERO_RS23065 in Herbaspirillum seropedicae SmR1

Annotation: psensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 475 transmembrane" amino acids 15 to 38 (24 residues), see Phobius details amino acids 171 to 193 (23 residues), see Phobius details PF00672: HAMP" amino acids 192 to 242 (51 residues), 54.4 bits, see alignment 1.9e-18 PF00512: HisKA" amino acids 248 to 311 (64 residues), 56.1 bits, see alignment E=4.8e-19 PF02518: HATPase_c" amino acids 356 to 467 (112 residues), 89.6 bits, see alignment E=2.8e-29

Best Hits

KEGG orthology group: K07642, two-component system, OmpR family, sensor histidine kinase BaeS [EC: 2.7.13.3] (inferred from 100% identity to hse:Hsero_4613)

Predicted SEED Role

"Sensory histidine kinase BaeS"

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IXV7 at UniProt or InterPro

Protein Sequence (475 amino acids)

>HSERO_RS23065 psensor histidine kinase (Herbaspirillum seropedicae SmR1)
LSDRFFYRANIRLKLFYAMLALIVALIAAINGAGHYIFNRDFLGYLNEQAQQRMEDMVPR
LEQAYREHGSWDFIRDNPRAWFELMKPAIVEHNGAARSAGPTFTASDLTGATLRFSLLDA
SRRPVIGYPNVGPDARLRPLLQDDVIIGWVAQTPFESVIGALDLRFQQSQFAAQIIIAVV
AVMLAAFLVVRISGVLTRPLTRVARATHRLASGDYAIRVEVESGDEVGMLAQDFNQLAMT
LERNEKLRREFMADVSHELRTPLAILNGQLEALEDGVLQPDAQTLRSLKSEVEHLNKLVG
DLYDLSLADAGALTYRRADIDLAPLLRDSAALYSDRFSQRGMRLSCELPASMPVHGDAAR
LQQLLSNLFENSLRYTDAGGRLQVHAHLQQQHWHLVFDDSEPGVPPEVMARLFERFFRVE
ASRNRASGGAGLGLAICRRIVDAHQGTIGASASPLGGLRVVVVLPARLEDERGSA