Protein Info for HSERO_RS22490 in Herbaspirillum seropedicae SmR1

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 475 transmembrane" amino acids 269 to 290 (22 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 307 to 473 (167 residues), 162.4 bits, see alignment E=4.1e-52 PF00990: GGDEF" amino acids 312 to 472 (161 residues), 154.8 bits, see alignment E=8.4e-50

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_4500)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IWS9 at UniProt or InterPro

Protein Sequence (475 amino acids)

>HSERO_RS22490 diguanylate cyclase (Herbaspirillum seropedicae SmR1)
MTATVSCAVLYQSHRQVERAAIEHGANIARIAQRSISRNVELLTLALDSLTWRYRHTQLH
EMPLQQKMEFLLGENIEARYVAALGIVDTDGELVVGSAALSQILPGPYAQSDFFTAHQTH
HAQGDTGLYISAPLTVRLERRMQVVVLSKRLAQPDGSFAGISLMVLYLDYFRDLFQGLTL
ENDGVISLYSADGLAYMRIPYNEAFIGSRLNISEDLERIFSPSGPAQGSYFARAQQDGPR
WLYTFARVPGTGWTVFIGRTGARIFREWYNMLYAVLFLMASFCIASIYLIRRVRVELQRR
SALDQQLEELARTDKLTSLLNRRALDEALARAWKRAEENPDAIFSLLFVDVDFFKLYNDT
YGHKAGDYALMAVSRCIVAAVSRLSDQSGRYGGEEFVVLLNGTDTVGATHVAKRIISAIQ
SLKIPHERSPFDILTVSIGVTSLLREHHSSIEDVVKDADAALYRAKQDGRNKHSL