Protein Info for HSERO_RS22465 in Herbaspirillum seropedicae SmR1

Annotation: sugar ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 518 TIGR02633: D-xylose ABC transporter, ATP-binding protein" amino acids 5 to 504 (500 residues), 890.8 bits, see alignment E=1.1e-272 PF00005: ABC_tran" amino acids 21 to 173 (153 residues), 107.8 bits, see alignment E=7.1e-35 amino acids 280 to 435 (156 residues), 83.9 bits, see alignment E=1.8e-27

Best Hits

Swiss-Prot: 78% identical to XYLG_PSEPF: Xylose import ATP-binding protein XylG (xylG) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: K10545, D-xylose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 100% identity to hse:Hsero_4495)

MetaCyc: 55% identical to xylose ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-33-RXN [EC: 7.5.2.10, 7.5.2.13]

Predicted SEED Role

"D-xylose transport ATP-binding protein XylG" in subsystem Xylose utilization

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17 or 7.5.2.10 or 7.5.2.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IWS4 at UniProt or InterPro

Protein Sequence (518 amino acids)

>HSERO_RS22465 sugar ABC transporter (Herbaspirillum seropedicae SmR1)
MSEYLLEMKGIVKSFGGVRALNGIDIKIRPGECVGLCGENGAGKSTLMKILSGVYPHGTW
EGEILWDGKPLQAHSVRDTEAAGIVIIHQELMLVPELSVAENIFMGHEITLPGGRMNYPA
MYRRAEELMRELNMPDINVALPVSQYGGGHQQLVEIAKALNKDARLLILDEPSSSLTASE
IGVLLKIIKDLKARGVACVYISHKLDEVAEVCDTISVIRDGKHIATTPMQEMDVDKIITQ
MVGREITAMYPERNHAIGEVVLEARNITCYDIDNPRRKRVDDVSFSVRRGEILGIAGLVG
AGRTELVSAIFGAYRGRYEGQVLLEGKPADTSSPLKSIRRGLCMVPEDRKHHGIVPDLDV
GQNITLTVLNRFSRGSRIDGSAELKTIQDEIGRMRVKTATPFLPITSLSGGNQQKAVLAK
MLLAQPKVLILDEPTRGVDVGAKAEIYRLISELAKAGLAIIMVSSELAEVLGVSDRVLVI
GEGRLRGDFVNDNLSQETVLAAAINQPVPQATPRAAAG