Protein Info for HSERO_RS22310 in Herbaspirillum seropedicae SmR1

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF00126: HTH_1" amino acids 6 to 62 (57 residues), 70 bits, see alignment E=1.3e-23 PF03466: LysR_substrate" amino acids 88 to 294 (207 residues), 133 bits, see alignment E=1e-42

Best Hits

Swiss-Prot: 38% identical to LYSRL_PSEAB: HTH-type transcriptional repressor PA14_22550 (PA14_22550) from Pseudomonas aeruginosa (strain UCBPP-PA14)

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_4464)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IVX2 at UniProt or InterPro

Protein Sequence (299 amino acids)

>HSERO_RS22310 LysR family transcriptional regulator (Herbaspirillum seropedicae SmR1)
MDQLLAIRAFARVVEAGNFTRAADSLDMPNATLSKLVRELEAHLGVRLLQRTTRRVSVTP
EGLDYYEKTGRLVRDLEDIDTSFNAARGNPRGKLRIDVGGSTARDVLIPALPDFLARYPD
ISIDLGVSDRPVDLIGDSVDCVIRGGPLDNSSLVARQIGQARMVTCATPAYLKQFGVPAY
PDELKNGHRLISYLSPQSGRAFPFRFERKGEKIEIKTEHRIGVNESNAHLAAALAGLGIV
QTFRYAAGPALARGELVEILTKWRPAPYPFHVVYPNNRHVSHRLRVFIDWLMAYLPAKF