Protein Info for HSERO_RS21770 in Herbaspirillum seropedicae SmR1

Annotation: arginyl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 PF03485: Arg_tRNA_synt_N" amino acids 8 to 94 (87 residues), 81.6 bits, see alignment E=7.7e-27 TIGR00456: arginine--tRNA ligase" amino acids 28 to 577 (550 residues), 426.2 bits, see alignment E=8.8e-132 PF00750: tRNA-synt_1d" amino acids 117 to 406 (290 residues), 83.9 bits, see alignment E=1.7e-27 PF05746: DALR_1" amino acids 459 to 577 (119 residues), 118.9 bits, see alignment E=1.9e-38

Best Hits

Swiss-Prot: 80% identical to SYR_HERAR: Arginine--tRNA ligase (argS) from Herminiimonas arsenicoxydans

KEGG orthology group: K01887, arginyl-tRNA synthetase [EC: 6.1.1.19] (inferred from 100% identity to hse:Hsero_4355)

Predicted SEED Role

"Arginyl-tRNA synthetase (EC 6.1.1.19)" (EC 6.1.1.19)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IVL5 at UniProt or InterPro

Protein Sequence (577 amino acids)

>HSERO_RS21770 arginyl-tRNA synthetase (Herbaspirillum seropedicae SmR1)
MLAQQKQRISDLFSSALQPLLAESGLTPTITLERPRDASHGDVACNIAMQLAKPLKKNPR
ELAQAIVAAVMADPAREDLVESVEIAGPGFINLRVAAAAKQAVVKVIHEQGEAYGRGSAG
AGKKVLVEFVSANPTGPLHVGHGRQGALGDALSSLLEAQGYDVLREFYYNDAGVQIATLA
TSVQARARGFKPGDAEWPESAYNGDYIADIARDFLDKKTVSASDGEPVTGSGEVDDIESI
RRFAVAYLRHEQDLDLQAFGVKFDNYYLESSLYADGKVAAAVDALIAAGKTYEQDGALWL
RTTDYGDDKDRVMKKTDGTYTYFVPDVAYHINKWQRGYGKVINIQGSDHHGTIARVRAGL
QAAGVGIPQGYPDYVLHKMVTVMRNGEEVKISKRAGSYVTLRDLIEWSAGEPVEGQERDL
TRGRDAVRFFLISRKADTEFVFDVDLALAQSDENPVYYVQYAHARICTVLGKSGVDEEAL
KSSADLSLLTAPREATLLAKLAEYPDMLAHALQELGPHQVAFYLRDLAGELHSYYNAERV
LVDDVPTRSARLALLSATRQVLRNGLALLGVSAPARM