Protein Info for HSERO_RS21710 in Herbaspirillum seropedicae SmR1

Annotation: antibiotic resistance protein MarC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 229 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 48 to 93 (46 residues), see Phobius details amino acids 126 to 146 (21 residues), see Phobius details amino acids 155 to 179 (25 residues), see Phobius details amino acids 192 to 213 (22 residues), see Phobius details TIGR00427: membrane protein, MarC family" amino acids 6 to 215 (210 residues), 110.4 bits, see alignment E=5e-36 PF01914: MarC" amino acids 8 to 218 (211 residues), 129.4 bits, see alignment E=6.2e-42

Best Hits

KEGG orthology group: K05595, multiple antibiotic resistance protein (inferred from 100% identity to hse:Hsero_4344)

Predicted SEED Role

"Multiple antibiotic resistance protein marC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IVK4 at UniProt or InterPro

Protein Sequence (229 amino acids)

>HSERO_RS21710 antibiotic resistance protein MarC (Herbaspirillum seropedicae SmR1)
MFILFLKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAI
FIGSHVLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIK
ARSFYPMSFPLTVGPGTIAASITLGANTPTRLLDWVISVGSAALGAALTALVIFLCYNYA
HKLVHLMGRLGTMVVLRLSAFILLCIGIQIFWSGMSALLAEAGISGVAP