Protein Info for HSERO_RS21155 in Herbaspirillum seropedicae SmR1

Annotation: HPr kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 PF07005: SBD_N" amino acids 8 to 232 (225 residues), 267.5 bits, see alignment E=1.2e-83 PF17042: NBD_C" amino acids 260 to 416 (157 residues), 158.5 bits, see alignment E=2.3e-50

Best Hits

Swiss-Prot: 76% identical to OTNK_BURM1: 3-oxo-tetronate kinase (otnK) from Burkholderia multivorans (strain ATCC 17616 / 249)

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_4233)

MetaCyc: 76% identical to 3-dehydrotetronate 4-kinase monomer (Cupriavidus necator H16)
RXN-18594 [EC: 2.7.1.217]; 2.7.1.217 [EC: 2.7.1.217]

Predicted SEED Role

"FIG00641944: hypothetical protein"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.217

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IUH0 at UniProt or InterPro

Protein Sequence (428 amino acids)

>HSERO_RS21155 HPr kinase (Herbaspirillum seropedicae SmR1)
MSTSRPLLGCIADDFTGATDLANMLVRGGMRTVQTIGVPAEMPAVAADALVIALKSRTVP
AAEAIAQSLAALRWLQQQGCTQFFFKYCSTFDSTDAGNIGPVTDALMKELGVDFTIACPA
FPENGRTIYRGYLFVADALLNESGMENHPLTPMTDANLVRVLQRQTESKVGLVRYDTVAR
GAAATQERFTALRSEGVKMAIADAVSDKDLFTLGEACAELKLITGGSGVALGLPENFRRA
GLLTAVGEAAQLPKVDGLSVVLAGSASKATNAQVAEWKAKRPAFRIDPLALARGEDVVAQ
ALAFADERIKNEPVLIYATATPDEVKAVQKELGVAKAGHLVEQALASIAAGLRQRGVRQF
VVAGGETSGAVVQALEVRALRIGPQIDPGVPATATLDDQPVALALKSGNFGSVDFFEKAL
RYLDGKTA