Protein Info for HSERO_RS20720 in Herbaspirillum seropedicae SmR1

Annotation: GMP synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 230 PF00005: ABC_tran" amino acids 18 to 166 (149 residues), 116.8 bits, see alignment E=6.1e-38

Best Hits

Swiss-Prot: 55% identical to FTSE_ECO57: Cell division ATP-binding protein FtsE (ftsE) from Escherichia coli O157:H7

KEGG orthology group: K09812, cell division transport system ATP-binding protein (inferred from 100% identity to hse:Hsero_4147)

MetaCyc: 42% identical to L-glutamine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-12-RXN [EC: 7.4.2.1]

Predicted SEED Role

"Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1)" in subsystem Bacterial Cell Division (TC 3.A.5.1.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8ITI7 at UniProt or InterPro

Protein Sequence (230 amino acids)

>HSERO_RS20720 GMP synthase (Herbaspirillum seropedicae SmR1)
MIEFTRVSKQYAREVYALRDITLSVRKGELIFLAGPSGAGKSTLLKMIAAIERPTAGKLA
VNGTDIGGLKASGLPYLRRNLGLIFQQQKLLLDRNLLSNVMLPLIVTGSSRQDAERRARA
ALDKVDLLGKAMCEPMELSGGEQQRVAIARAIVNRPQIILADEPTANLDRANANKVLAAL
KSFHGVGVTCLISTHDEQFLTGADRIIYLDRGRIVDGWHNGVANPVEVSP