Protein Info for HSERO_RS20525 in Herbaspirillum seropedicae SmR1

Annotation: alpha-glucosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 803 PF13802: Gal_mutarotas_2" amino acids 29 to 218 (190 residues), 120.5 bits, see alignment E=1.7e-38 PF01055: Glyco_hydro_31_2nd" amino acids 265 to 592 (328 residues), 301.2 bits, see alignment E=1.6e-93 PF21365: Glyco_hydro_31_3rd" amino acids 601 to 687 (87 residues), 86.6 bits, see alignment E=2e-28

Best Hits

KEGG orthology group: K01187, alpha-glucosidase [EC: 3.2.1.20] (inferred from 100% identity to hse:Hsero_4108)

Predicted SEED Role

"Alpha-glucosidase (EC 3.2.1.20)" in subsystem D-Galacturonate and D-Glucuronate Utilization or Maltose and Maltodextrin Utilization (EC 3.2.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8ITE8 at UniProt or InterPro

Protein Sequence (803 amino acids)

>HSERO_RS20525 alpha-glucosidase (Herbaspirillum seropedicae SmR1)
MSMLHPPRFALQSSEGNHLCLKADTGAVIELFVLEEDIIRVLVLPEGKLQGPASWAVAPG
AEDVPLQGRDRRDLSGFALPSFALRTTPGQLQIETALIRLSIALEGGFCQWELRQEGQWQ
SVLADRPTQAYNFGYWDEQVYHYLRRQPEEMYFGLGERAGDMNRAGQSYEMRNIDAMGYS
ARNTDPLYKHIPFYITWLPKTGAGFGLFYDTLSDCRFDMGRELDNYHGHYRYFTAPHGDL
DYYFIASPGTPLAATRRFTWLTGRPAWMPKWGLGYSGSTMSYTDAPDAQVQMGQFIAKCR
EHDILCDSFHLSSGYTSIGPKRYVFHWNTEKFPDPHGFVRSYLDASIHLCANIKPCLLRD
HPQFEQARQAGLLICDSQGEPAWVQFWDEVGAYLDFTNPATLDWWRANVKQALLDYGVSA
TWNDNNEFEVWTGDAYAHGFGQQYPVRQAKVLQTMLMMQASRQAQLEAAPQRRPFLVSRS
GGAGMQRYVQTWSGDNYTSWETLRYNLKMGLGLALSGVSNIGHDIGGFSGPAPAPELLVR
WVAFGVFMPRFSIHSWNDDKTVNEPWMYPEVTAQIAALIKLRYRFIPYLYELLWQSTQDY
QPVLRPTFAEFPHDRRCLDECDDMMLGSAMLVAPVVEQGQTERRVYLPSGARWVSYWSGE
RYEGGQEISLPAPWDQPVMLLREGAVIPMNVAQQQFDVRADERAFLVVPYKEQGEASGAC
VEDDGHSQAWRDGEQGRWQVRARSDAAAVTLEVGREDRLPVAAETIDIFLPASEQRPVRA
TQARIVSEQRSQGWRRLTLALST