Protein Info for HSERO_RS20285 in Herbaspirillum seropedicae SmR1

Annotation: twin-arginine protein translocation system subunit TatC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 transmembrane" amino acids 24 to 49 (26 residues), see Phobius details amino acids 71 to 98 (28 residues), see Phobius details amino acids 111 to 140 (30 residues), see Phobius details amino acids 160 to 183 (24 residues), see Phobius details amino acids 195 to 213 (19 residues), see Phobius details amino acids 219 to 239 (21 residues), see Phobius details TIGR00945: twin arginine-targeting protein translocase TatC" amino acids 13 to 229 (217 residues), 217.2 bits, see alignment E=1.3e-68 PF00902: TatC" amino acids 14 to 224 (211 residues), 228 bits, see alignment E=5.5e-72

Best Hits

Swiss-Prot: 48% identical to TATC_HAEIN: Sec-independent protein translocase protein TatC (tatC) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K03118, sec-independent protein translocase protein TatC (inferred from 100% identity to hse:Hsero_4057)

MetaCyc: 49% identical to twin arginine protein translocation system - TatC protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-181

Predicted SEED Role

"Twin-arginine translocation protein TatC" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8ISW1 at UniProt or InterPro

Protein Sequence (256 amino acids)

>HSERO_RS20285 twin-arginine protein translocation system subunit TatC (Herbaspirillum seropedicae SmR1)
MAEENTQAEDTFISHLIELRSRIVKAAAVVLVVFLCMMPFAAHIFDVLAAPMIHALPAGS
KMIATGVITPFLIPIKVTMLVAVLVSLPWVLYQLWAFVAPGLYTHEKRLIAPLVISSSVL
FVAGVAFCYFFVFGVVFPFINNFAPKSVSVAPDIDSYVDFVLTMFVAFGVTFEVPVIVIV
LVRMGLVPLAKLKQVRPYVIVGAFIIAAVVTPPDVMSQLMLAVPLVLLYEVGLLVAPIFE
RATQAPATEAGSSTSD