Protein Info for HSERO_RS19810 in Herbaspirillum seropedicae SmR1

Annotation: excinuclease ABC subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 952 TIGR00630: excinuclease ABC subunit A" amino acids 4 to 932 (929 residues), 1466 bits, see alignment E=0 PF17760: UvrA_inter" amino acids 131 to 243 (113 residues), 120.2 bits, see alignment E=1.1e-38 PF17755: UvrA_DNA-bind" amino acids 294 to 403 (110 residues), 124.6 bits, see alignment E=6.5e-40

Best Hits

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 67% identity to aat:D11S_0457)

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8ISL9 at UniProt or InterPro

Protein Sequence (952 amino acids)

>HSERO_RS19810 excinuclease ABC subunit A (Herbaspirillum seropedicae SmR1)
MEEIRIRGARTHNLKNINLDLPRNKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAY
ARQFLQLMEKPDVDMIEGLSPAISIEQKATSHNPRSTVGTVTEIHDYLRLLYARVGTPYC
PDHPEHPLEAQSVSQMVDAVLALPEDTKLMIMAPVVANRKGEHADLFEEMQAQGFVRFRI
QSGTGTAKVYEVDDLPKLKKTEKHTIDVVIDRVKVKADIKQRLAESFETALRLADGRAIA
LEMDSGKEHLYSNKFACPICGYSLQELEPRLFSFNNPMGACPECDGLGHIEFFDPKRIVA
FPNLSLASGAIKGWDRRNQFYFQMLTSIAAYYGFDLDVPFEQLDDKAQQAVLYGSGRQTI
PFAYVNERGRTVVKEHTFEGVVNNLQRRYRETDSMAVKEELAKFINEKQCPSCHGARLRV
EARYVKVGSGKQQRAIYEVAATPLRETLSFFETLKLTGAKKEIADRIIKEIVSRLTFLNN
VGLDYLSLERSADTLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLIDTLK
HLRDIGNTVLVVEHDEDAIRTADYVVDMGIGAGVHGGDVIAHGPLPDILKNKKSLTAKYL
NGSLEIAVPKKRTPCDESRMLTISGATGNNLKNVDLELPVGLLTCVTGVSGSGKSTLVND
TLYLSAARHLYGSQTEPAAHEAIGGLEHFDKVIAVDQAPIGRTPRSNPATYTGLFTPIRD
LFATVPMAKERGYSAGRFSFNVKGGRCEACQGDGVIKVEMHFLPDVYVPCDVCHGKRYNR
ETLEVQYKGKNITEILDMTVEDAHEFFKPVPLIARKLQTLLDVGLGYIKLGQSATTLSGG
EAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDIDLLLKVIHRLRDQGNTVTIIEHNLD
VIKTADWIIDLGPEGGAGGGRIVAAGTPEEVAKNPASVTGKYLAPLLKKKSK