Protein Info for HSERO_RS17335 in Herbaspirillum seropedicae SmR1

Annotation: ribose 5-phosphate isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 223 TIGR00021: ribose 5-phosphate isomerase A" amino acids 6 to 219 (214 residues), 234.1 bits, see alignment E=5.9e-74 PF06026: Rib_5-P_isom_A" amino acids 49 to 217 (169 residues), 206.7 bits, see alignment E=1e-65

Best Hits

Swiss-Prot: 83% identical to RPIA_HERAR: Ribose-5-phosphate isomerase A (rpiA) from Herminiimonas arsenicoxydans

KEGG orthology group: K01807, ribose 5-phosphate isomerase A [EC: 5.3.1.6] (inferred from 100% identity to hse:Hsero_3462)

MetaCyc: 64% identical to ribose-5-phosphate isomerase A (Escherichia coli K-12 substr. MG1655)
Ribose-5-phosphate isomerase. [EC: 5.3.1.6]

Predicted SEED Role

"Ribose 5-phosphate isomerase A (EC 5.3.1.6)" in subsystem Calvin-Benson cycle or D-ribose utilization or Pentose phosphate pathway (EC 5.3.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IPP5 at UniProt or InterPro

Protein Sequence (223 amino acids)

>HSERO_RS17335 ribose 5-phosphate isomerase (Herbaspirillum seropedicae SmR1)
MTQDELKQAVAKAAIEYVVDGEIIGVGTGSTANFFIDELGKIKHRIKGAVASSEATAERL
RSHGITVFDLNEVETMPVYIDGADEINGGGAMIKGGGAALTREKIVASVAQKFVCIADGS
KLVEVLGKFPLPVEVIPMSHAVVARKLAALGGEPRLRVKDGKPVVTDNGCYIIDVLGLSI
TDPADVEDKINNIVGVVTNGLFARQGANVCLLGTADGVKKLEF