Protein Info for HSERO_RS16630 in Herbaspirillum seropedicae SmR1

Annotation: sodium:proton antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 31 to 52 (22 residues), see Phobius details amino acids 83 to 104 (22 residues), see Phobius details amino acids 115 to 136 (22 residues), see Phobius details amino acids 157 to 178 (22 residues), see Phobius details amino acids 184 to 205 (22 residues), see Phobius details amino acids 217 to 234 (18 residues), see Phobius details amino acids 240 to 258 (19 residues), see Phobius details amino acids 279 to 300 (22 residues), see Phobius details amino acids 313 to 338 (26 residues), see Phobius details amino acids 359 to 385 (27 residues), see Phobius details amino acids 397 to 420 (24 residues), see Phobius details TIGR00831: Na+/H+ antiporter" amino acids 7 to 550 (544 residues), 446.3 bits, see alignment E=7e-138 PF00999: Na_H_Exchanger" amino acids 9 to 422 (414 residues), 225.4 bits, see alignment E=5.6e-71

Best Hits

KEGG orthology group: K03316, monovalent cation:H+ antiporter, CPA1 family (inferred from 100% identity to hse:Hsero_3320)

Predicted SEED Role

"Na+/H+ antiporter" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8J218 at UniProt or InterPro

Protein Sequence (560 amino acids)

>HSERO_RS16630 sodium:proton antiporter (Herbaspirillum seropedicae SmR1)
MEIVFTVLILLLAVAVSGVVARLAPFKLPLPLFQIALGAVLALPMFGLRISFDPELFLLL
FIPPLLFTDGWRMPKREFFRLARPILALALGLVMFTVVGVGYFIHWMIPVISLPSAFALA
AVLSPTDAVAVSSIVGKGRLPASMQHVLEGEALMNDASGLVAFKFAIAAVITGTFSLLDA
SISFVLIAAGGVAVGLIVAWGFGLIRRKIIEWAGDEPGIQVVLLLLIPFTAYIFAEHFGL
SGILGAVAAGMLMPYLETAGGESAATRLQGRSIMTMLEFVFNGMSFLLLGLQLPGIVSLA
HMDAKMAGNVPVWHLFVYIVAITLALVVLRFVWVWINLRMRRFASALRGQSGRNRKFDLR
LISITALSGVRGAITLAGVMSIPLLLKEHTPFPARDLLIFLATGVIVCSLLLGSLLLPWM
LKDLQLDAEVKRRRAEEMMARLRLSEAAVRSIETAQERIGMNLDENDLALLTEVSGSLLA
TYRMRMNAESDSEETQRAANRFKQFERELRLEAIRAERLEVHYLRAEQRINDETFLMLIN
QIDMAETWLLGSLNAPGQHH