Protein Info for HSERO_RS16605 in Herbaspirillum seropedicae SmR1
Annotation: oxidoreductase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 37% identical to YHXC_BACSU: Uncharacterized oxidoreductase YhxC (yhxC) from Bacillus subtilis (strain 168)
KEGG orthology group: K00059, 3-oxoacyl-[acyl-carrier protein] reductase [EC: 1.1.1.100] (inferred from 100% identity to hse:Hsero_3315)MetaCyc: 35% identical to aldehyde reductase (chloroplastic) (Arabidopsis thaliana col)
Aldehyde reductase. [EC: 1.1.1.21]; Alcohol dehydrogenase (NADP(+)). [EC: 1.1.1.21, 1.1.1.2]; 1.1.1.2 [EC: 1.1.1.21, 1.1.1.2]; 1.1.1.- [EC: 1.1.1.21, 1.1.1.2]; 1.1.1.- [EC: 1.1.1.21, 1.1.1.2]
Predicted SEED Role
"3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)" in subsystem Fatty Acid Biosynthesis FASII or mycolic acid synthesis (EC 1.1.1.100)
MetaCyc Pathways
- superpathway of fatty acids biosynthesis (E. coli) (50/53 steps found)
- superpathway of fatty acid biosynthesis II (plant) (38/43 steps found)
- palmitate biosynthesis II (type II fatty acid synthase) (29/31 steps found)
- superpathway of unsaturated fatty acids biosynthesis (E. coli) (19/20 steps found)
- oleate biosynthesis IV (anaerobic) (13/14 steps found)
- palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) (9/9 steps found)
- superpathway of fatty acid biosynthesis I (E. coli) (14/16 steps found)
- biotin biosynthesis I (13/15 steps found)
- cis-vaccenate biosynthesis (5/5 steps found)
- fatty acid elongation -- saturated (5/5 steps found)
- gondoate biosynthesis (anaerobic) (4/4 steps found)
- 8-amino-7-oxononanoate biosynthesis I (9/11 steps found)
- (5Z)-dodecenoate biosynthesis I (5/6 steps found)
- stearate biosynthesis II (bacteria and plants) (5/6 steps found)
- 8-amino-7-oxononanoate biosynthesis IV (4/5 steps found)
- octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) (9/12 steps found)
- palmitate biosynthesis III (21/29 steps found)
- (5Z)-dodecenoate biosynthesis II (4/6 steps found)
- stearate biosynthesis IV (4/6 steps found)
- anteiso-branched-chain fatty acid biosynthesis (24/34 steps found)
- even iso-branched-chain fatty acid biosynthesis (24/34 steps found)
- odd iso-branched-chain fatty acid biosynthesis (24/34 steps found)
- methylglyoxal degradation III (1/2 steps found)
- tetradecanoate biosynthesis (mitochondria) (17/25 steps found)
- D-arabinose degradation V (1/3 steps found)
- L-arabinose degradation II (1/3 steps found)
- glycerol degradation to butanol (10/16 steps found)
- pyruvate fermentation to butanol I (4/8 steps found)
- superpathway of methylglyoxal degradation (4/8 steps found)
- D-xylose degradation to ethylene glycol (engineered) (1/4 steps found)
- L-tryptophan degradation X (mammalian, via tryptamine) (1/4 steps found)
- petroselinate biosynthesis (2/6 steps found)
- detoxification of reactive carbonyls in chloroplasts (4/10 steps found)
- 2-allylmalonyl-CoA biosynthesis (2/8 steps found)
- superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation (8/17 steps found)
- superpathway of Clostridium acetobutylicum solventogenic fermentation (5/13 steps found)
- streptorubin B biosynthesis (20/34 steps found)
- traumatin and (Z)-3-hexen-1-yl acetate biosynthesis (3/12 steps found)
- superpathway of pentose and pentitol degradation (19/42 steps found)
- superpathway of lipoxygenase (4/22 steps found)
- mycolate biosynthesis (25/205 steps found)
- superpathway of mycolate biosynthesis (26/239 steps found)
KEGG Metabolic Maps
- Biosynthesis of unsaturated fatty acids
- Caprolactam degradation
- Fatty acid biosynthesis
- Fructose and mannose metabolism
- Galactose metabolism
- Glycerolipid metabolism
- Glycolysis / Gluconeogenesis
- Pentose and glucuronate interconversions
- Pyruvate metabolism
Isozymes
Compare fitness of predicted isozymes for: 1.1.1.100
Use Curated BLAST to search for 1.1.1.100 or 1.1.1.2 or 1.1.1.21
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See D8J213 at UniProt or InterPro
Protein Sequence (253 amino acids)
>HSERO_RS16605 oxidoreductase (Herbaspirillum seropedicae SmR1) MLDLAGKVVFISGASTGIGAAAARAFAARGSHLVVHYNSSEKEAEAVAAEVRAAGSKSIT IGADVRDTSAINAAVAKAVAQMGRIDVLINNAGALVKRAPLETVTDELFDDIININARSV VAFTRAVIPVMRAQGGGNIINVTSVAARHGGGPGALIYAASKGFVSTLTRGMAKELLADK IRVNAVAPGVIMTPFQERFTTPEQLEGFRKTIPMGRIGEPDECSGAFLYLASEQMSGYVT GQIIDVNGGQYMP