Protein Info for HSERO_RS16020 in Herbaspirillum seropedicae SmR1

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 PF00027: cNMP_binding" amino acids 70 to 153 (84 residues), 60 bits, see alignment E=2.8e-20 PF13545: HTH_Crp_2" amino acids 188 to 262 (75 residues), 63.6 bits, see alignment E=2e-21 PF00325: Crp" amino acids 213 to 244 (32 residues), 53.5 bits, see alignment 2.4e-18

Best Hits

Swiss-Prot: 44% identical to BTR_BORPE: Transcriptional regulatory protein btr (btr) from Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)

KEGG orthology group: K01420, CRP/FNR family transcriptional regulator, anaerobic regulatory protein (inferred from 100% identity to hse:Hsero_3197)

Predicted SEED Role

"transcriptional regulator, Crp/Fnr family" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8J1B0 at UniProt or InterPro

Protein Sequence (278 amino acids)

>HSERO_RS16020 transcriptional regulator (Herbaspirillum seropedicae SmR1)
MNQSCHSTPITTPANAAAPLTHCSSLTAAREAAASSALRSCTACGMHQLCLPMGLDESDM
KRLDKIIGRRKVARDDFLYRIGDRFTALYAVRVGHFKTYQENLDGDRQITGFQMPGELLG
MDAISTEQHQCDAVALQDSEVCEIPFARLEQLFGQIPHLLRHFHRIMSHEITSEQNVIML
LGNMRAEQRFAAFLVNLSSRYAARGYSSTRFQLRMTRQDVGNYLGLTIESISRLISKFRK
QGLLAVEQRDVEVVDLAALKRLAAGVDACTATPTRSTS