Protein Info for HSERO_RS15980 in Herbaspirillum seropedicae SmR1

Annotation: DSBA oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 522 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 64 to 83 (20 residues), see Phobius details amino acids 91 to 114 (24 residues), see Phobius details amino acids 122 to 140 (19 residues), see Phobius details amino acids 152 to 172 (21 residues), see Phobius details amino acids 178 to 201 (24 residues), see Phobius details amino acids 213 to 232 (20 residues), see Phobius details amino acids 246 to 264 (19 residues), see Phobius details amino acids 285 to 304 (20 residues), see Phobius details amino acids 318 to 336 (19 residues), see Phobius details amino acids 345 to 362 (18 residues), see Phobius details amino acids 374 to 393 (20 residues), see Phobius details amino acids 419 to 431 (13 residues), see Phobius details amino acids 491 to 510 (20 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 29 to 509 (481 residues), 353.2 bits, see alignment E=1.2e-109 PF07690: MFS_1" amino acids 32 to 424 (393 residues), 158.7 bits, see alignment E=9.9e-51

Best Hits

KEGG orthology group: K03446, MFS transporter, DHA2 family, multidrug resistance protein B (inferred from 100% identity to hse:Hsero_3188)

Predicted SEED Role

"Inner membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8J1A1 at UniProt or InterPro

Protein Sequence (522 amino acids)

>HSERO_RS15980 DSBA oxidoreductase (Herbaspirillum seropedicae SmR1)
VSSAPAKPMAAAGANGEKADAAAWLAVAAGTLGALMATLDISIVNSSLPTIQGEIGASGT
EGTWIATAYLVAEIVIIPMSAWLERLLGLRVLLLTAASLFTLFSVLCGLSTTLPMMIVGR
VGQGFTGGALIPTAMTIIATRLPRSQQPVGNAMFGATAILGPVLGPVMGGWLTENVSWHY
AFFINLPVGAALITLLLVAIPYERPKFEQLAEADWFGIAGLALGLGGLTVVLEEGEREQW
FSSPDIRWLAATSVLGFILLAIGQVRARHPVIQLRLLRDRQFGSVVMMAMIVGVALYGTA
YVIPQFLSGIAGYNSLQSGWIVLLSGVPMILMMPFTPLLMRLVDIRIAVGTGFLLLAASA
FIETDLSPLSYGGSFVASQLMRGVGTVLAMLFLNQAAIRSVPPSQAGDASGLYSAARNLG
GSLALAAIAVIQDQRLWLHSRRLEESLNANSDLVQSSMTAQGHLLGGQDVALQLMGATIQ
SQALTMTYADLFWMLGVAILCVTPLVLFLRPLPTHAAPVASH