Protein Info for HSERO_RS15745 in Herbaspirillum seropedicae SmR1

Annotation: molecular chaperone HscA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 621 TIGR01991: Fe-S protein assembly chaperone HscA" amino acids 21 to 619 (599 residues), 933.8 bits, see alignment E=2.1e-285 PF00012: HSP70" amino acids 21 to 603 (583 residues), 627.5 bits, see alignment E=2.1e-192 PF06723: MreB_Mbl" amino acids 121 to 375 (255 residues), 52.6 bits, see alignment E=3.4e-18

Best Hits

Swiss-Prot: 84% identical to HSCA_HERAR: Chaperone protein HscA homolog (hscA) from Herminiimonas arsenicoxydans

KEGG orthology group: K04044, molecular chaperone HscA (inferred from 100% identity to hse:Hsero_3139)

Predicted SEED Role

"Chaperone protein HscA" in subsystem Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8J154 at UniProt or InterPro

Protein Sequence (621 amino acids)

>HSERO_RS15745 molecular chaperone HscA (Herbaspirillum seropedicae SmR1)
MALLQISEPGMSTAPHQRRLAVGIDLGTTNSLVATVRNSIPEVLADDDGRVLLPSVVRYL
PNGHANIGYKAQAAQTTDPRNTIVSVKRFMGRGLKDIAHAENMPYDFQDQPGMVQIKTVA
GVKSPVEVSAQILATLRQTAEDALGDDLVGAVITVPAYFDDAQRQATKDAAQLAGLNVLR
LLNEPTAAAIAYGLDNSSEGVFAVYDLGGGTFDISILKLTRGVFEVLATGGDSALGGDDF
DHRLFCWISHEAQLQPLSDEDTRLLMVKAREVKELLSTKDEVQIDAVLRSGEEVHLSITA
AQFNEITQHLVAKTMAPVRKALRDAGLTVEDVDGVVLVGGATRMPHIRRAVGEFFKTNPL
SNIDPDKVVALGAAVQANLLAGNRAPGDDWLLLDVIPLSLGIETMGGLAEKVIPRNSTIP
CARAQEFTTFKDGQTAMAIHVVQGERELVADCRSLARFELRGIPPMAAGAARIRVTYQVD
ADGLLAVSAREMTSGVEASITVKPSYGLGDDEIARMLQESFSSADEDMQRRALREEQVEA
ERIVLATRSALQADAALLSEAERQAIEAQVEAVSAAAQGTDHLAIKAAVDALAHGTEEFA
ARRMDRSVHAALAGKKLDEVA