Protein Info for HSERO_RS15670 in Herbaspirillum seropedicae SmR1

Annotation: major facilitator transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 transmembrane" amino acids 29 to 50 (22 residues), see Phobius details amino acids 57 to 82 (26 residues), see Phobius details amino acids 92 to 112 (21 residues), see Phobius details amino acids 116 to 116 (1 residues), see Phobius details amino acids 118 to 146 (29 residues), see Phobius details amino acids 159 to 179 (21 residues), see Phobius details amino acids 191 to 210 (20 residues), see Phobius details amino acids 242 to 262 (21 residues), see Phobius details amino acids 274 to 295 (22 residues), see Phobius details amino acids 307 to 326 (20 residues), see Phobius details amino acids 332 to 357 (26 residues), see Phobius details amino acids 372 to 393 (22 residues), see Phobius details amino acids 404 to 424 (21 residues), see Phobius details PF00083: Sugar_tr" amino acids 24 to 221 (198 residues), 75.7 bits, see alignment E=5.4e-25 amino acids 222 to 413 (192 residues), 28.3 bits, see alignment E=1.3e-10 PF07690: MFS_1" amino acids 28 to 304 (277 residues), 83.9 bits, see alignment E=1.6e-27 amino acids 280 to 422 (143 residues), 51.5 bits, see alignment E=1.1e-17 PF13347: MFS_2" amino acids 152 to 397 (246 residues), 37.2 bits, see alignment E=2e-13

Best Hits

KEGG orthology group: K03762, MFS transporter, MHS family, proline/betaine transporter (inferred from 100% identity to hse:Hsero_3123)

Predicted SEED Role

"Citrate-proton symporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8J138 at UniProt or InterPro

Protein Sequence (427 amino acids)

>HSERO_RS15670 major facilitator transporter (Herbaspirillum seropedicae SmR1)
MSSNTAAPGADITHPQARRAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLL
LTFATFGVSFFMRPLGAVVLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYASIGLLA
PAGIALGKMIQGFSAGGEFGSSTAFLVEHAPHRRGFFSSWQVASQGISLLLAALFGAVLN
NMLTPEQLASWGWRVPFIFGLLIAPAGIYIRRHLDEAPEFKESSEKTNAPLRDTFAHQKM
RLLIGAGSVIMATVSVYLSLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSD
KIGRTPFMITSSALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADI
FPVATRGTGMSLAYNIAVTIFGGFAGLIITWLIDFTGDKLSVSYFVIFGAVLSLIASLSA
RLVLRLR